Results 101 to 110 of about 5,065,330 (358)

Clinical research practice [PDF]

open access: yes, 1998
published_or_final_versio
Karlberg, JPE, Lui, WF, Tsang, K
core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Effectiveness of positive allosteric modulators of metabotropic glutamate receptor 2/3 (mGluR2/3) in animal models of schizophrenia

open access: yesTranslational Psychiatry
Schizophrenia (SZ) is a deleterious brain disorder characterised by its heterogeneity and complex symptomatology consisting of positive, negative and cognitive deficits.
David Olivares-Berjaga   +6 more
doaj   +1 more source

A non-interventional switch study in adult patients with asthma or COPD on clinical effectiveness of salmeterol/fluticasone Easyhaler® in routine clinical practice [PDF]

open access: gold, 2021
Ines Vinge   +8 more
openalex   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Promoting Hope, Healing, and Wellness: Catholic Interventions in Behavioral Health Care [PDF]

open access: yes, 2018
In this chapter, we will outline, highlight, and review some of the Catholic traditions and pastoral tools that can be integrated into any professional clinical practice in behavioral health care.
Manuel, Gerdenio, S.J., Plante, Thomas G
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Chinese expert consensus statement on metformin in clinical practice

open access: yesChinese Medical Journal, 2020
Expert Group of Metformin in Clinical Practice   +1 more
doaj   +1 more source

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