Results 121 to 130 of about 18,067,200 (315)

KDIGO Clinical Practice Guidelines for Acute Kidney Injury

Nephron Clinical Practice, 2012
A. Khwaja
semanticscholar   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Behavioral Determinants of Leadership Engagement in Health Profession Students: A Cross-Sectional Study Using the Theoretical Domains Framework (TDF)

Journal of Healthcare Leadership
Alla El-Awaisi,1 Menatallah Rayan,1 Dhabya Mohamed Al-Khater,2 Derek Stewart,1 Mohammed Al-Hamdani,3 Myriam Jaam,1 Mohammad Issam Diab1 1Clinical Pharmacy and Practice Department, College of Pharmacy, QU Health, Qatar University, Doha, Qatar; 2Hamad ...
El-Awaisi A, Rayan M, Al-Khater DM, Stewart D, Al-Hamdani M, Jaam M, Diab MI   +6 more
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Ultrasound education, competencies and expected future use among medical interns in Denmark: a national cross-sectional study

BMC Medical Education
Background Point-of-care ultrasound is increasingly used across medical specialties, calling for timely and relevant ultrasound education in specialty training.
Pernille Gram, Thomas Purup, Emilie Marie Eriksen, Stina Søbye, Simone Kjaergaard Wielandt, Kasper Astorp, Martin Bach Jensen, Camilla Aakjaer Andersen   +7 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

ESMO Clinical Practice Guideline for the diagnosis, staging and treatment of patients with metastatic breast cancer.

Annals of Oncology, 2021
A. Gennari, F. André, C. Barrios, J. Cortés, E. de Azambuja, A. Demichele, R. Dent, D. Fenlon, J. Gligorov, S. Hurvitz, S. Im, D. Krug, W. Kunz, S. Loi, F. P. Lorca, J. Ricke, M. Robson, H. Rugo, C. Saura, P. Schmid, C. Singer, T. Španić, S. Tolaney, N. Turner, G. Curigliano, S. Loibl, S. Paluch-Shimon, N. Harbeck   +27 more
semanticscholar   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

2016 European Guidelines on cardiovascular disease prevention in clinical practice.

Revista Española de Cardiología, 2016
M. Piepoli, A. Hoes, S. Agewall, C. Albus, C. Brotons, A. Catapano, M. Cooney, U. Corrà, B. Cosyns, Christi Deaton, I. Graham, Michael Stephen Hall, F. R. Hobbs, M. Løchen, H. Löllgen, P. Marques-Vidal, J. Perk, E. Prescott, J. Redón, D. Richter, N. Sattar, Y. Smulders, M. Tiberi, H. B. Worp, I. V. Dis, W. Verschuren   +25 more
semanticscholar   +1 more source

Efficacy of Paroxetine as an Adjuvant Therapy in Rheumatoid Arthritis Patients: A Randomized Controlled Study

Drug Design, Development and Therapy
Khlood Mohammad Aldossary,1 Mahmoud S Abdallah,2,3 Esraa M Mosalam,3,4 Noha Kamal,2 Dalia S Saif,5 Sahar Abdel-Rahman Elsayed,6 Naglaa Afifi,7 Haitham G Zakaraia,2 Mohannad O Khrieba,8 Mostafa M Bahaa8,9 1Department of Pharmacy Practice, College of ...
Aldossary KM, Abdallah MS, Mosalam EM, Kamal N, Saif DS, Elsayed SAR, Afifi N, Zakaraia HG, Khrieba MO, Bahaa MM   +9 more
doaj