Results 181 to 190 of about 15,567,398 (344)

Pharmacists' perspectives on integrating pharmacogenetics in clinical practice. [PDF]

open access: yesHum Genomics
Hatem NAH   +5 more
europepmc   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Brain compliance: a new assessment for clinical practice? [PDF]

open access: yesFront Cardiovasc Med
Saraiva LS   +3 more
europepmc   +1 more source

Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

open access: yesAnnals of Oncology, 2022
E. Smyth   +5 more
semanticscholar   +1 more source

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