Results 181 to 190 of about 11,694,642 (308)

Prevalence and Factors Associated with Albuminuria Screening Among High-Risk Adults in Saudi Arabia: A Retrospective Cross-Sectional Study

open access: yesInternational Journal of Nephrology and Renovascular Disease
Mohamed A Albekery,1 Mohammed Alnuhait,2 Ibrahim S Alhomoud,3 Khalid Alhussain,1 Munirah K Alkulaib,4 Gharam M Alanazi,5 Zainab F Alshaikh,1 Fatimah S Alibrahim,1 Kawthar Y Alburayman,1 Ghadeer H Alhajji,1 Bassem A Almalki,6 Ibrahim F Aldossary,7 Lulwah ...
Albekery MA   +13 more
doaj  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Clinical Characteristics, Antifungal Therapy, and Outcomes of Candida auris Candidemia: A Two-Center Cohort Study

open access: yesInfection and Drug Resistance
Reem Binsuwaidan,1 Layan W Alshalhoub,2 Nada Mabruk Almesfer,2 Sara Almuhisen,3 Osama A Alzuman,3 Alnada Ibrahim,4 Yahya A Mohzari,5 Ahmed A Alrashed,3 Reem F Bamogaddam,5 Seham Elbih,6,7 Abdulaziz Ageel ALAgeel,6 Abeer Odah AlMazyad,6 Ohoud Awadhallah ...
Binsuwaidan R   +18 more
doaj  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Decrypting network physiology for clinical practice. [PDF]

open access: yesFront Netw Physiol
Munson R   +4 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A Randomized Controlled Pilot Study Evaluating the Safety and Efficacy of Nifuroxazide in Patients with Ulcerative Colitis

open access: yesDrug Design, Development and Therapy
Hayam Ali AlRasheed,1 Mahmoud S Abdallah,2,3 Eman El-Khateeb,4,5 Marwa Kamal,6 Sarah Alrubia,7 Amsha S Alsegiani,7 Tarek I Ahmed,8 Mostafa M Bahaa9 1Department of Pharmacy Practice, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh,
AlRasheed HA   +7 more
doaj  

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