Results 191 to 200 of about 2,133,135 (297)

A potential tumor suppressor role of PLK2 in glioblastoma

open access: yesFEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia   +5 more
wiley   +1 more source

Reactive Pleocytosis After Repeated Lumbar Puncture-Implications for Clinical Practice. [PDF]

open access: yesEur J Neurol
Schmidauer M   +13 more
europepmc   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Correction to: Pilot comparative effectiveness study of surface perturbation treadmill training to prevent falls in older adults

open access: yesBMC Geriatrics, 2022
Jon D. Lurie   +4 more
doaj   +1 more source

Pharmacogenomic of LH and its receptor: are we ready for clinical practice? [PDF]

open access: yesReprod Biol Endocrinol
Conforti A   +4 more
europepmc   +1 more source

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

open access: yesFEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma   +3 more
wiley   +1 more source

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