Results 161 to 170 of about 11,705,271 (311)

A Guide for the Inclusion of Sex and Gender Considerations in Clinical Practice Guidelines. [PDF]

Clin Public Health Guidel
King T, Ervin J, Sitohang MY, Dalziel K, Tew M, Tannenbaum C, Maheen H.   +6 more
europepmc   +1 more source

Standardized Reporting of Clinical Practice Guidelines: A Proposal From the Conference on Guideline Standardization

, 2003
Despite enormous energies invested in authoring clinical practice guidelines, the quality of individual guidelines varies considerably. The Conference on Guideline Standardization (COGS) was convened in April 2002 to define a standard for guideline ...
Shiffman, Richard N., Overhage, J. Marc, Grimshaw, Jeremy, Slutsky, Jean, Shekelle, Paul, Deshpande, Aniruddha M.   +5 more
core  

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Closing the Guideline Gap

JACC: Advances
Rohan G. Reddy, BS, David A. Danford, MD, MPH, Andreas Schuster, MD, PhD, MBA, Shelby Kutty, MD, PhD, MHCM   +3 more
doaj   +1 more source

Update of Korean Medicine Clinical Practice Guidelines for Obesity Management: An Evidence-Based GRADE Approach. [PDF]

Obesity (Silver Spring)
Kim SD, Son MJ, Kim BY, Ko MM, Jegal KH, Kim H, Park SH, Kim KW, Song MY, Jo J, Kim H, Shin WC, Kim T, Zhao H, Yang C, Chung WS, Kim S.   +16 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Message for Clinical Practice Guidelines

Indian Journal of Psychiatry, 2020
Vinay Kumar
doaj   +1 more source

Perspectives on sex and gender inclusion in clinical practice guidelines: a qualitative study. [PDF]

BMJ Open
Maheen H, Ervin J, Sitohang MY, King T.
europepmc   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source