Results 101 to 110 of about 1,341,814 (306)

Comparison of real world and core laboratory lupus anticoagulant results from the Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION) clinical database and repository [PDF]

, 2019
BackgroundVariability remains a challenge in lupus anticoagulant (LA) testing.ObjectiveTo validate LA test performance between Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION) Core laboratories and examine ...
Bison, Elisa, Ugarte, Amaia, Vega, Joann, Erkan, Doruk, Sevim, Ecem, Cohen, Hannah, Belmont, H. Michael, Tektonidou, Maria, Knight, Jason S., Borges Galhardo Vendramini, Margarete, Cervera, Ricard, Knight, Jason S, Andrade, Danieli, Branch, D. Ware, Branch, D Ware, Ji, Lanlan, Mackie, Ian J, Atsumi, Tatsuya, Andreoli, Laura, Chighizola, Cecilia, Fortin, Paul R, Jesus, Guilherme, Rodriguez, Esther, Aguirre, Maria Angeles, Mackie, Ian J., Romay‐penabad, Zurina, Petri, Michelle, Efthymiou, Maria, Willis, Rohan, Fortin, Paul R., Belmont, H Michael, Krillis, Steven, de Jesus, Guilherme, Pengo, Vittorio, Bertolaccini, Maria Laura, Romay-Penabad, Zurina, Lane, Philip J., Qi, Miao, Lane, Philip J, Sciascia, Savino   +39 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Development and validation of a nursing care protocol for pregnant women and newborns in Brazil [PDF]

Journal of Research Development in Nursing and Midwifery
Background: The standards for the care of women and newborns are a collaborative plan of care based on the prioritization of diagnoses, problems, health issues, and mutually established goals, involving the interprofessional team, the patient, their ...
Eny Dorea, Luana de Almeida Juca, Clisangela Lago Santos, Valdecyr Herdy Alves, Sheley Borges Gadelha de Lima   +4 more
doaj  

Clinical and radiological results of patients treated with two loading protocols for mandibular overdentures on Brånemark implants

, 2006
Objective: The aim of this study was to evaluate clinical and radiological outcomes of the unsplinted implants supporting mandibular overdenture when applying conventional or early loading protocols.
Turkyilmaz, Ilser,, Ilser Turkyilmaz, Turkyilmaz, I   +2 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Protocols of Thiamine Supplementation: Clinically Driven Rationality vs. Biological Commonsense

Background: Thiamine deficiency requires supplementation to prevent or reverse severe clinical complications. Are supplementation protocols correctly tailored in neurology?
Mickael Bonnan
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Twenty Years of Advancements in a Radiotherapy Facility: Clinical Protocols, Technology, and Management. [PDF]

Curr Oncol, 2023
Tomatis S, Mancosu P, Reggiori G, Lobefalo F, Gallo P, Lambri N, Paganini L, La Fauci F, Bresolin A, Parabicoli S, Pelizzoli M, Navarria P, Franzese C, Lenoci D, Scorsetti M.   +14 more
europepmc   +1 more source

Multi-Level Verification of Clinical Protocols

, 1998
. In the medical domain, clinical practice guidelines and protocols build a commonly accepted way to improve patient health care. During the last years various approaches have been presented to support the computerization of such guidelines and protocols.
Georg Duftschmid, Silvia Miksch
core