Results 111 to 120 of about 2,012,129 (303)

The treatment of epilepsy in developing countries: where do we go from here?

Bulletin of the World Health Organization
Epilepsy is the most common serious neurological disorder and is one of the world’s most prevalent noncommunicable diseases. As the understanding of its physical and social burden has increased it has moved higher up the world health agenda.
Robert A. Scott, Samden D. Lhatoo, Josemir W.A.S. Sander   +2 more
doaj   +1 more source

Health care providers' knowledge of clinical protocols for postpartum hemorrhage care in Kenya: a cross-sectional study. [PDF]

BMC Pregnancy Childbirth, 2022
Henry J, Clarke-Deelder E, Han D, Miller N, Opondo K, Oguttu M, Burke T, Cohen JL, McConnell M.   +8 more
europepmc   +1 more source

Protocols for clinical use at Nature Protocols [PDF]

Nature Protocols, 2021
openaire   +2 more sources

Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong.

, 2003
BACKGROUND: Health authorities worldwide, especially in the Asia Pacific region, are seeking effective public-health interventions in the continuing epidemic of severe acute respiratory syndrome (SARS).
Abu-Raddad, Laith J, Anderson, Roy M, Chan, King-Pan, Chau, Patsy, Donnelly, Christl A, Ferguson, Neil M, Fraser, Christophe, Ghani, Azra C, Hedley, Anthony J, Ho, Lai-Ming, Kong, James HB, Lam, Tai-Hing, Lau, Edith MC, Leung, Gabriel M, Liu, Shao-Haei, Riley, Steven, Thach, Thuan-Quoc, Tsang, Thomas, Tse, Lai-Yin   +18 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Optimal clinical protocols for total-body 18F-FDG PET/CT examination under different activity administration plans. [PDF]

EJNMMI Phys, 2023
Huang Y, Wang M, Jiang L, Wang L, Chen L, Wang Q, Feng J, Wang J, Xu W, Wu H, Han Y.   +10 more
europepmc   +1 more source

Transmission dynamics of the etiological agent of SARS in Hong Kong: impact of public health interventions.

, 2003
We present an analysis of the first 10 weeks of the severe acute respiratory syndrome (SARS) epidemic in Hong Kong. The epidemic to date has been characterized by two large clusters-initiated by two separate "super-spread" events (SSEs)-and by ongoing ...
Abu-Raddad, Laith J, Anderson, Roy M, Chan, King-Pan, Chau, Patsy, Donnelly, Christl A, Ferguson, Neil M, Fraser, Christophe, Ghani, Azra C, Hedley, Anthony J, Ho, Lai-Ming, Ho, William, Lam, Tai-Hing, Lau, Edith MC, Lee, Koon-Hung, Leung, Gabriel M, Leung, Pak-Yin, Lo, Su-Vui, Riley, Steven, Thach, Thuan Q, Tsang, Thomas   +19 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Use of a digital job-aid in improving antenatal clinical protocols and quality of care in rural primary-level health facilities in Burkina Faso: a quasi-experimental evaluation. [PDF]

BMJ Open, 2023
Maïga A, Ogyu A, Millogo RM, Lopez-Hernandez A, Labité MA, Labrique A, Agarwal S.   +6 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source