Results 81 to 90 of about 1,974,839 (304)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Decentralised Clinical Guidelines Modelling with Lightweight Coordination Calculus

, 2007
Background: Clinical protocols and guidelines have been considered as a major means to ensure that cost-effective services are provided at the point of care.
Dasmahapatra, Srinandan, Hu, Bo, Lewis, Paul, Robertson, Dave   +3 more
core  

An evaluation of enteral nutrition practices and nutritional provision in children during the entire length of stay in critical care [PDF]

, 2014
<b>Background</b> Provision of optimal nutrition in children in critical care is often challenging. This study evaluated exclusive enteral nutrition (EN) provision practices and explored predictors of energy intake and delay of EN ...
A Slater, AF Rousseau, C Lambe, David Young, DO Health, EJ Rogers, Emma Gentles, GC Briassoulis, GS Doig, GS Doig, H Woien, Hani A Alfheeaid, IM Mitchell, J Hulst, Jackie Mara, JL Vazquez Martinez, JM Hulst, JM Hulst, Konstantinos Gerasimidis, Krystalia Diamantidi, LF Lima, MA Holliday, Mark Davidson, MM Pollack, Neil Spenceley, NM de, R Meyer, RM Taylor, SB de Oliveira Iglesias, T Petrillo-Albarano, TA Mikhailov, TJ Cole, WN Schofield   +32 more
core   +3 more sources

CT Examinations for COVID-19: A Systematic Review of Protocols, Radiation Dose, and Numbers Needed to Diagnose and Predict

대한영상의학회지, 2021
Purpose Although chest CT has been discussed as a first-line test for coronavirus disease 2019 (COVID-19), little research has explored the implications of CT exposure in the population.
Jong Hyuk Lee, Hyunsook Hong, Hyungjin Kim, Chang Hyun Lee, Jin Mo Goo, Soon Ho Yoon   +5 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Clinical trial metadata:Defining and extracting metadata on the design, conduct, results and costs of 125 randomised clinical trials funded by the National Institute for Health Research Health Technology Assessment programme [PDF]

, 2015
Background:  By 2011, the Health Technology Assessment (HTA) programme had published the results of over 100 trials with another 220 in progress. The aim of the project was to develop and pilot ‘metadata’ on clinical trials funded by the HTA programme.  
Cook, Andrew, Davidson, Peter, Milne, Ruairidh, Raftery, James, Stanton, Louise, Turner, David, Young, Amanda   +6 more
core   +2 more sources

Comprehensive Analysis of Different Subtypes of Oxylipins to Determine a LC–MS/MS Approach in Clinical Research

Metabolites
Background/Objectives: Different oxylipin subtypes have unique biological properties, requiring effective analytical protocols. However, establishing a complete pathway detection protocol for comprehensive oxylipin analysis is challenging.
Yurou Zhao, Zhengyu Fang, Zeyu Li, Yizhe Liu, Yang Bai, Xiaoqing Wang, Hongjun Yang, Na Guo   +7 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Context-based task ontologies for clinical guidelines [PDF]

, 2004
Evidence-based medicine relies on the execution of clinical practice guidelines and protocols. A great deal of of effort has been invested in the development of various tools which automate the representation and execution of the recommendations ...
Ciccarese, Paolo, Kumar, Anand, Piazza, Matteo, Smith, Barry   +3 more
core  

Ethics, space, and somatic sensibilities: comparing relationships between scientific researchers and their human and animal experimental subjects [PDF]

, 2011
Drawing on geographies of affect and nature-society relations, we propose a radical rethinking of how scientists, social scientists, and regulatory agencies conceptualise human and animal participants in scientif ic research. The scientific rationale for
Birke L, Boo M J, Buchanan-Smith H M, Butler R, Calarco M, Ehni H, FAWC, Fenwick N P, Grandin T, Grosz E, Haraway D, Harlow H, Hinchliffe S, Jones O, Katz J, Keller E F, Latour B, Lawler J, Leach M, Lorimer J, Nast H J, Paterson M, RCN, RCN, Roe E, Rudge T, Russell W M S, Singer P, Stengers I, Thrift N, Vorstenbosch J M C, Wemelsfelder F, Whatmore S, Wolfe C   +33 more
core   +1 more source