Results 111 to 120 of about 494,249 (301)

10 tips for clinical educators in designing and delivering learning experiences to improve clinical reasoning for medical students. [version 3; peer review: 2 approved]

MedEdPublish
Background Clinical reasoning processes involve gathering and interpreting information, creating differential diagnoses and testing hypotheses to inform and guide patient management.
Charlotte Deng, Kelvin Le, Khang Duy Ricky Le   +2 more
doaj   +1 more source

The role of clinician emotion in clinical reasoning: balancing the analytical process

IntroductionThis review paper identifies and describes the role of clinicians' memory, emotions and physical responses in clinical reasoning processes.
Langridge, Neil, Pope, Catherine, Roberts, Lisa   +2 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Does online case-based learning foster clinical reasoning skills? A mixed-methods study

Future Healthcare Journal
Background: Blended learning, integrating face-to-face and virtual methods, has become essential in clinical education, enhancing student satisfaction, engagement and knowledge outcomes.
Jun Jie Lim, Bhavani Veasuvalingam
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Logical model of Personality and Cognition with possible Applications [PDF]

, 2016
Although the cognition is significant in strategic reasoning, its role has been weakly analyzed, because only the average intelligence is usually considered.
Brada, Miro
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Psychometric characteristics of clinical reasoning problems (CRPs) and its correlation with routine multiple choice question (MCQ) in cardiology department

Journal of Advances in Medical Education and Professionalism, 2018
Introduction: Clinical reasoning is one of the most important skills in the process of training a medical student to become an efficient physician.
ZAHRA DERAKHSHANDEH, MITRA AMINI, JAVAD KOJURI, MARZIYEH DEHBOZORGIAN   +3 more
doaj  

Teaching clinical reasoning to medical students: A brief report of case-based clinical reasoning approach

Journal of Education and Health Promotion
BACKGROUND: Case-based clinical reasoning (CBCR) is the proposed method to improve clinical reasoning. This brief report aimed to evaluate CBCR effectiveness to improve clinical reasoning via an online course.
Mostafa Alavi-Moghaddam, Arman Zeinaddini-Meymand, Soleiman Ahmadi, Aryan Shirani   +3 more
doaj   +1 more source