Results 161 to 170 of about 9,750,898 (317)

Clinical significance of annexin A2 heterotetramer in sepsis. [PDF]

Blood Vessel Thromb Hemost
Lim HI, Hajjar KA.
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Emergency CT KUB: Incidental Findings and Their Clinical Significance. [PDF]

Open Access Emerg Med
Dayraki M, Anjum S, AlKhulaifi L, Miranda L, Mohmmad DAM, Jabeen A, Bhutta ZA, Yigit Y.   +7 more
europepmc   +1 more source

Clinical Significance of Jaundice

International Journal of Clinical Practice, 1957
openaire   +2 more sources

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Clinical Significance of a Cell-Of-Origin-Based Classification in Pancreatic Ductal Adenocarcinoma. [PDF]

Cancer Sci
Kikuchi T, Ako S, Kato H, Kinugasa H, Uchida M, Oda T, Hirai R, Matsumi A, Miyamoto K, Terasawa H, Fujii Y, Uchida D, Matsumoto K, Tsutsumi K, Horiguchi S, Yasui K, Fuji T, Takagi K, Kato H, Honda T, Otsuka F, Otsuka M.   +21 more
europepmc   +1 more source

The clinical significance of statins-macrolides interaction: comprehensive review of in vivo studies, case reports, and population studies

, 2019
Abdallah Abu Mellal,1 Nadia Hussain,2 Amira SA Said21College of Health and Human Sciences, Charles Darwin University, Darwin, Northern Territory, Australia; 2College of Pharmacy, Al Ain University of Science and Technology, Al Ain, UAEAbstract: The ...
Abu Mellal A, Said ASA, Hussain N
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Multidimensional roles and clinical significance of GATA3 in breast cancer. [PDF]

Front Cell Dev Biol
Tan J, Chen W, Song K, Zhu X, Hong L, Zhou J, Chen K, Lv H.   +7 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source