Results 181 to 190 of about 9,750,898 (317)

Atrial Fibrillation Burden: Assessment, Clinical Significance, and Therapeutic Implications. [PDF]

Life (Basel)
Grigoriou K, Lamprou V, Ktenopoulos N, Theofilis P, Iliakis P, Vlachakis PK, Apostolos A, Antoniadis AP, Fragakis N, Karakasis P.   +9 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Clinical significance of resting and dobutamine stress myocardial work in cirrhotic cardiomyopathy. [PDF]

Echo Res Pract
Ramachandran J, Pati PK, Mohammadi F, Jospeh M, Hecker T, Chinnaratha MA, Gunton J, Muller K, Chapman M, Woodman R, Wigg A.   +10 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Hepatic Steatosis in People With Chronic Hepatitis B in Africa: Prevalence, Correlates, and Clinical Significance. [PDF]

J Viral Hepat
Chabala FW, Sinkala E, Brennan AT, Goss AM, Bojang L, Samateh Y, Stockdale AJ, Sombie R, Sessouma A, Guingane AN, Goungounga JA, El-Kassas M, Marwan E, Diallo I, Sow A, Okeke E, Okwute A, Prozesky H, Ismail Z, Sonderup M, Spearman CW, Matthews PC, Tine JM, Lemoine M, Mekonnen HD, Johnannessen A, Vinikoor MJ, Hepatitis B in Africa Collaborative Network (HEPSANET).   +27 more
europepmc   +1 more source

THE CLINICAL SIGNIFICANCE OF CAVERNOLITHIASIS

Journal of Thoracic Surgery, 1953
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Longitudinal dynamics and clinical significance of acetylcholine receptor blocking antibodies in myasthenia gravis. [PDF]

Neurol Sci
Vakrakou AG, Belimezi M, Strataki E, Kontizas E, Tzavella D, Panaretos D, Angelakis E, Zouvelou V.   +7 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Monoclonal gammopathy of clinical significance: a multisystem review. [PDF]

Blood Cancer J
Sra MS, Rajkumar SV, Kumar S.
europepmc   +1 more source