Results 191 to 200 of about 2,602,365 (264)

Editorial Comment on Beyond Total PSA: Clinical Significance of S2,3PSA% in Reducing Unnecessary Prostate Biopsies. [PDF]

Int J Urol
Goto Y.
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Clinical significance of HPV DNA and EGFR mutations in Egyptian NSCLC. [PDF]

Infect Agent Cancer
Saeed Mohamed S, Hassan ZK, Fahmy AM, Youssef ASE, Fattah NFA, Khater AI, Soliman HK, Hafez MM.   +7 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

The clinical significance of circulating microRNAs as biomarkers in lung cancer diagnosis and prognosis. [PDF]

Discov Oncol
Fan J, Shen D, He L, Yan C, Li H, Zhang Y, Bai X.   +6 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The clinical significance and prognostic implication of autophagy-related gene 13 in human gastric cancer. [PDF]

Front Oncol
You Y, Li W, Feng Y, Gao L, Li T, Zhang X, Luo X.   +6 more
europepmc   +1 more source

Clinical Significance of MYBL2 Expression in Hepatocellular Carcinoma: Impact on Overall Survival. [PDF]

Onco Targets Ther
Chen CC, Wei CT, Hsuan CF, Yu TH, Hung WC, Wu CC, Lee TL, Tang WH, Chung FM, Lee YJ, Hsu CC.   +10 more
europepmc   +1 more source