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Statistical Significance Versus Clinical Significance
Seminars in Cardiothoracic and Vascular Anesthesia, 2008Unfortunately, the data were statistically nonsignificant due to insufficient power and poor experimental design. Conversely, many large clinical trials obtain a high level of statistical significance with miniscule differences between groups, which are completely clinically irrelevant.
Timothy T, Houle, David A, Stump
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The Clinical Significance of Macrocytosis
Acta Medica Scandinavica, 1981ABSTRACT. The cause of macrocytosis (mean corpuscular volume (MCV) ≥105 fl) was investigated over a period of 16 months in the 70 known cases of ± 4000 patients seen by the Department of Internal Medicine. By means of simple laboratory investigations the cause of elevated MCV was found in more than 90% of the cases.
F C, Breedveld +2 more
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The Clinical Significance of Hypouricemia
Annals of Internal Medicine, 1973The development of automated techniques in the clinical laboratory which routinely include the measurement of uric acid has raised important questions concerning the clinical significance of abnormal serum urate values. Although numerous studies have focused on the relevance of hyperuricemia, the possible significance of hypouricemia has not been ...
C M, Ramsdell, W N, Kelley
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Measures of Clinical Significance
Journal of the American Academy of Child & Adolescent Psychiatry, 2003Behavioral scientists are interested in answering three basic questions when examining the relationships between variables (Kirk, 2001). First, is an observed result real or should it be attributed to chance (i.e., statistical significance)? Second, if the result is real, how large is it (i.e., effect size)?
Helena Chmura, Kraemer +5 more
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The Clinical Significance of Hematuria
The American Journal of Nursing, 1954Hematuria is not a disease but a symptom; it cna occur in association with systemic disease, with intrinsic disease of the genitourinary tract, or with disease localized in other parts of the body. In the author's experience, the nature of the underlying cause varied strikingly with age.
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Clinical Significance of Hypertriglyceridemia
Seminars in Thrombosis and Hemostasis, 1988Available data suggest that elevated triglyceride levels in plasma, associated with increased VLDL or chylomicron remnants, are associated with premature coronary artery atherosclerosis. Whether this is a direct effect or as a result of the association of hypertriglyceridemia with decreased HDL as well as decreased LDL particle size remains to be ...
E J, Schaefer +3 more
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The clinical significance of kinekard
The American Journal of Cardiology, 1967Abstract A survey of plasma kinekard concentration in 32 normal individuals and 220 patients suffering from a variety of diseases has been made. While abnormal levels may be found in many diseases, patients with various cardiovascular and pituitary-hypothalamic syndromes give readings clearly different from other diseases. A significant correlation
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CLINICAL SIGNIFICANCE OF BACTEROIDES
Archives of Internal Medicine, 1949CERTAIN anaerobic, nonsporing, gram-negative bacilli are classified in the genus Bacteroides. 1 (Excluded from this designation are the genera Dialister and Fusiformis, the former being characterized by small size and the latter by pointed ends.) These organisms are saprophytic inhabitants of the intestine, the urinary tract, the pharynx and the female
P M, BEIGELMAN, L A, RANTZ
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THE CLINICAL SIGNIFICANCE OF JAUNDICE
JAMA: The Journal of the American Medical Association, 1927Excerpt Theories in the matter of jaundice and ideas, coming from the laboratory or the bedside, that contemplate the physiology and the pathology of bile pigment as anything other than an affair o...
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Dusts of Clinical Significance
Diseases of the Chest, 1949Although many dusts may cause disability in isolated instances and many others may prove to be of considerable significance upon further investigation, the one dust of great and known hazards is silica. The other chemically related dust, asbestos, is known to cause great disability.
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