Results 81 to 90 of about 4,364,564 (311)

Molecular pathogenesis and targeted therapy of sporadic pancreatic neuroendocrine tumors [PDF]

, 2015
Over the past few years, knowledge regarding the molecular pathology of sporadic pancreatic neuroendocrine tumors (PNETs) has increased substantially, and a number of targeted agents have been tested in clinical trials in this tumor type.
Ahn, Balogh, Bergers, Berruti, Capurso, Capurso, Carew, Castellano, Chamberlain, Chan, Chan, Chen, Clynes, Corbo, Corbo, Couvelard, De Wilde, Di Florio, Di Florio, Di Florio, Fazio, Fendrich, Gaur, Gurung, Han, Heaphy, Heaphy, Hobday, Hopfner, House, Jacinto, Jensen, Jiao, Karnik, Karnik, Komori, Kulke, Laplante, Loewith, Lovejoy, Luzi, Marinoni, Marion-Audibert, Mendel, Meric-Bernstam, Missiaglia, Mocellin, Panzuto, Papouchado, Passacantilli, Perren, Pàez-Ribes, Raymond, Sarbassov, Scoazec, Shah, Shi, Tang, Vinagre, Wang, Yang, Yao, Yuan, Zhang, Zhang   +64 more
core   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

Clinical significance of elevated tumor markers in patients with biliary pancreatitis

Frontiers in Medicine
ObjectiveThis study explores the clinical significance of elevated tumor markers in patients with biliary pancreatitis. It aims to develop a machine learning-based clinical prediction model to facilitate early intervention and improve outcomes in acute ...
He Han, Zhiyuan Li, Yunfan Li, Liwen Zhang, Jixiang Chen, Xin Fan   +5 more
doaj   +1 more source

The radial plot in meta-analysis : approximations and applications [PDF]

, 2009
Fixed effects meta-analysis can be thought of as least squares analysis of the radial plot, the plot of standardized treatment effect against precision (reciprocal of the standard deviation) for the studies in a systematic review.
Copas, John B., Lozada-Can, Claudia
core   +1 more source

Inpatient Food Insecurity and Pediatric Hematology Oncology Hospitalization Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Children with cancer and blood disorders are at risk for food insecurity (FI). We aimed to describe the association of inpatient food insecurity (IFI) and hospitalization outcomes among patients admitted to the pediatric hematology oncology service. Of 325 caregivers screened for IFI, 60 (18.6%) screened positive.
Joanna M. Robles, Greg Russell, Leila H. DeWitt, Kimberly Montez, Callie L. Brown   +4 more
wiley   +1 more source

Clinicopathological significance and prognostic values of claudin18.2 expression in solid tumors: a systematic review and meta-analysis

Frontiers in Oncology
ObjectiveClaudin18.2 has been established as a putative therapeutic target in human solid malignancies. The aim of this study is to determine claudin18.2 expression as a clinicopathological and prognostic factor in human solid tumors through a systematic
Gyerim Park, Se Jun Park, Younghoon Kim
doaj   +1 more source

Noteworthy prognostic value of phospholipase C delta genes in early stage pancreatic ductal adenocarcinoma patients after pancreaticoduodenectomy and potential molecular mechanisms

Cancer Medicine, 2020
The purpose of this investigation was to explore the prognostic value of phospholipase C delta (PLCD) genes in early stage pancreatic ductal adenocarcinoma (PDAC) and its potential molecular mechanisms.
Xin Zhou, Xiwen Liao, Xiangkun Wang, Ketuan Huang, Chengkun Yang, Tingdong Yu, Chuangye Han, Guangzhi Zhu, Hao Su, Quanfa Han, Zijun Chen, Jianlv Huang, Yizhen Gong, Guotian Ruan, Xinping Ye, Tao Peng   +15 more
doaj   +1 more source

Optimizing Vancomycin Dosing in Chronic Kidney Disease by Deriving and Implementing a Web-Based Tool Using a Population Pharmacokinetics Analysis. [PDF]

, 2019
Background: Chronic kidney disease (CKD) patients requiring intravenous vancomycin bear considerable risks of adverse outcomes both from the infection and vancomycin therapy itself, necessitating especially precise dosing to avoid sub- and ...
Chae, Jung-Woo, Chan, Alexandre, Dorajoo, Sreemanee Raaj, Goh, Jessica Hui Fen, Lee, Siok Ying, Ooi, Say Tat, Somani, Jyoti, Winata, Chrystal Leandra, Yap, Chun Wei, Yeoh, Lee Ying   +9 more
core  

Copy number variations in healthy subjects. Case study: iPSC line CSSi005-A (3544) production from an individual with variation in 15q13.3 chromosome duplicating gene CHRNA7 [PDF]

, 2018
CHRNA7, encoding the neuronal alpha7 nicotinic acetylcholine receptor (a7nAChR), is highly expressed in the brain, particularly in the hippocampus. It is situated in the 15q13.3 chromosome region, frequently associated with a Copy Number Variation (CNV),
Altieri, Filomena, Bernardini, Laura, Della Monica, Matteo, Ferrari, Daniela, Goldoni, Marina, Lamorte, Giuseppe, Mazzoccoli, Gianluigi, Postorivo, Diana, Rosati, Jessica, Tata, Ada Maria, Torres, Barbara, Turco, Elisa Maria, Vescovi, Angelo Luigi, Vinci, Ersilia   +13 more
core   +1 more source

This Is Not a Myeloproliferative Neoplasm…

Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source