Results 91 to 100 of about 2,866,404 (318)

Functional analysis and clinical significance of the isocitrate dehydrogenase 2 gene in papillary thyroid carcinoma

, 2019
Jun Zhang,1–4 Linfei Hu,2–5 Huijuan Wang,2–5 Jingtai Zhi,2–5 Xiukun Hou,2–5 Yu Wu,6 Xiangqian Zheng,2–5 Ming Gao2–51Department of Breast Surgery, Tianjin Medical University Cancer Institute and Hospital, Tianjin ...
Zhi J, Zheng X, Gao M, Zhang J, Hu L, Wang H, Hou X, Wu Y   +7 more
core  

TRAP1 Shows Clinical Significance in the Early Diagnosis of Small Cell Lung Cancer

, 2021
Xiaohang Li,1 Xu Li,1 Simei Chen,1 Yang Wu,1 Yuhan Liu,1 Tingting Hu,1 Jiayi Huang,1 Jianlin Yu,1 Zihuan Pei,1 Tingting Zeng,2 Liming Tan1 1Department of Clinical Laboratory, The Second Affiliated Hospital of Nanchang University, Jiangxi Province Key ...
Tan L, Li X, Liu Y, Hu T, Huang J, Pei Z, Chen S, Yu J, Wu Y, Zeng T   +9 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Course and Relation of the Facial Vessels—An Anatomical Study

Medicina
Background and Objectives: Facial vascular anatomy plays a pivotal role in both physiological context and in surgical intervention. While data exist on the individual course of the facial artery and vein, to date, the spatial relationship of the ...
Martin Siwetz, Hannes Widni-Pajank, Niels Hammer, Simon Bruneder, Andreas Wree, Veronica Antipova   +5 more
doaj   +1 more source

The clinical significance of CCBE1 expression in human colorectal cancer

, 2018
Yan-Rong Zhao,1 Hao Liu,2 Li-Miao Xiao,3 Can-Guang Jin,1 Zhi-Peng Zhang,1 Chun-Guang Yang4 1Department of General Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China; 2Department of General Surgery, The Second Xiangya Hospital ...
Liu H, Jin CG, Xiao LM, Yang CG, Zhao YR, Zhang ZP   +5 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Unveiling the intratumor microbiome in liver cancer: Current insights and prospective applications [PDF]

Clinical and Molecular Hepatology
The role of the gut microbiome in the development and progression of liver cancer has long been recognized. However, the presence of microbes in tumors that were previously considered sterile has only recently been discovered.
Xindi Ke, Shangze Jiang, Qiaoxin Wei, Minghao Sun, Hang Sun, Mingchang Pang, Mei Liu, Lejia Sun, Huayu Yang, Yilei Mao   +9 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

STAT4 gene polymorphisms in human diseases

Frontiers in Immunology
Signal transducer and activator of transcription 4 (STAT4) is a member of the STAT family, which is a group of transcription factors that regulate cytokine signaling. Genetic polymorphisms in STAT4 strongly influence immune responses and disease outcomes,
Yan Xia, Yan Xia, Yanni Xie, Hao Zhang, Hao Zhang, Lunzhi Liu   +5 more
doaj   +1 more source

Neopterin in patients with early rheumatoid arthritis

Научно-практическая ревматология, 2008
62 pts with early rheumatoid arthritis (RA) were included. Neopterin changes dependence on RA clinical course and duration, acute phase markers (ESR, CRP) changes, presence of IgG and IgM rheumatoid factors, autoantibodies against cyclic citrullinated ...
N. V. Lysak, O. V. Bugrova
doaj   +1 more source