Results 41 to 50 of about 60,673,388 (296)

A CLINICAL STUDY OF MYOCARDITIS. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1901
It happens in every one's experience that at particular times clinical observation is specially rich in a single direction. So it has seemed to me that during the past year there have been under observation, both in hospital and private practice, a great number of cases in which the heart muscle seemed to be primarily at fault.
openaire   +2 more sources

PD-1/PD-L1 immune checkpoint inhibitors in glioblastoma: clinical studies, challenges and potential

open access: yesHuman Vaccines & Immunotherapeutics, 2020
Immune checkpoint inhibitors (CIs) have changed the landscape of tumor immunotherapy. Glioblastoma (GBM) remains the most common primary malignant brain tumor in adults and has a very poor prognosis. Due to the high invasiveness and aggressiveness of GBM,
Tian-Rui Yang, Z. Kong, Wen-Bin Ma
semanticscholar   +1 more source

Piperine-A Major Principle of Black Pepper: A Review of Its Bioactivity and Studies

open access: yesApplied Sciences, 2019
Piperine is the main compound present in black pepper, and is the carrier of its specific pungent taste, which is responsible for centuries of human dietary utilization and worldwide popularity as a food ingredient.
Zorica Stojanović-Radić   +7 more
doaj   +1 more source

Anticancer Drug Discovery Based on Natural Products: From Computational Approaches to Clinical Studies

open access: yesBiomedicines
Globally, malignancies cause one out of six mortalities, which is a serious health problem. Cancer therapy has always been challenging, apart from major advances in immunotherapies, stem cell transplantation, targeted therapies, hormonal therapies ...
Pritee Chunarkar-Patil   +9 more
semanticscholar   +1 more source

Photodynamic therapy for cancer: mechanisms, photosensitizers, nanocarriers, and clinical studies

open access: yesMedComm
Photodynamic therapy (PDT) is a temporally and spatially precisely controllable, noninvasive, and potentially highly efficient method of phototherapy. The three components of PDT primarily include photosensitizers, oxygen, and light. PDT employs specific
Wanchen Zhao   +8 more
semanticscholar   +1 more source

Evidence Base of Clinical Studies on Qi Gong: A Bibliometric Analysis.

open access: yesComplementary Therapies in Medicine, 2020
OBJECTIVE This bibliometric study aimed to systematically and comprehensively summarize the volume, breadth and evidence for clinical research on Qigong. And this bibliometric analysis also can provide the evidence of this field.
Ya-peng Zhang   +8 more
semanticscholar   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Assessment of the influence of demographic and anthropometric indicators on the variability of pharmacokinetic parameters

open access: yesФармакокинетика и Фармакодинамика
Relevance. Planning the design of bioequivalence clinical studies of generic highly variable drugs requires non-standard approaches – the use of replicative (repeated) or adaptive design.
V. B. Vasilyuk   +3 more
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan   +18 more
wiley   +1 more source

Prospective clinical trial analyzing serum mast cell tryptase levels and arthrofibrosis rates after total knee arthroplasty

open access: yesBone & Joint Research
Aims: Arthrofibrosis affects a notable percentage of patients after total knee arthroplasty (TKA). Elevated serum mast cell tryptase (SMCT) levels have been linked to fibrosis, suggesting that SMCT could serve as a biomarker for arthrofibrosis.
Nils Meissner   +7 more
doaj   +1 more source

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