Results 51 to 60 of about 9,880,911 (259)

Clinical Studies Target Fewer Complications, Better Outcomes for Vascular Surgery [PDF]

open access: yes, 2017
Two studies at the Jefferson Vascular Center (JVC) are assessing innovative methods to reduce risk of complications — and increase positive outcomes — for vascular surgery patients. Here, Paul DiMuzio, MD, FACS, William M. Measey Professor of Surgery and

core   +1 more source

The utility of home-practice in mindfulness-based group interventions: a systematic review [PDF]

open access: yes, 2016
A growing body of research supports the efficacy of mindfulness-based interventions (MBIs). MBIs consider home-practice as essential to increasing the therapeutic effects of the treatment.
Ana Baumann (3552509)   +4 more
core   +6 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Current regulatory requirements for clinical trials of viral vaccines

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. In recent years, the development of various vaccines based on novel platforms has underscored the significance of updating regulatory requirements for vaccines.
A. A. Soldatov   +3 more
doaj   +1 more source

Security oriented e-infrastructures supporting neurological research and clinical trials [PDF]

open access: yes, 2007
The neurological and wider clinical domains stand to gain greatly from the vision of the grid in providing seamless yet secure access to distributed, heterogeneous computational resources and data sets.
Ajayi, O.   +3 more
core   +3 more sources

Current regulatory approaches for accessing potential COVID-19 therapies

open access: yesJournal of Pharmaceutical Policy and Practice, 2020
This commentary aims to elaborate challenges in the regulatory approaches for accessing and investigating COVID-19 potential therapies either with off-label use, compassionate use, emergency use or for clinical trials.
Vesa Halimi   +6 more
doaj   +1 more source

Methodological Approaches to Studying Fatal Adverse Drug Reactions

open access: yesБезопасность и риск фармакотерапии, 2022
Serious adverse drug reactions (ADRs) to medicinal products can cause death. It is an immediate challenge for modern medicine to prevent the possibility of this outcome and to improve the safety of pharmacotherapy.
I. L. Asetskaya   +2 more
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Rationale and Design of a Prospective, Multicenter, Observational Study Evaluating Iron Deficiency in Patients Hospitalized for Heart Failure (FERIC-RO)

open access: yesRomanian Journal of Laboratory Medicine, 2018
Introduction: Several landmark studies, which enrolled heart failure (HF) patients who were ambulatory at the time of inclusion, identified iron deficiency (ID) as an important therapeutic target: intravenous iron administration with ferric ...
Antohi Elena Laura   +10 more
doaj   +1 more source

Telemedicine infectious diseases consultations and clinical outcomes: A systematic review [PDF]

open access: yes, 2019
Background: Telemedicine use is increasing in many specialties, but its impact on clinical outcomes in infectious diseases has not been systematically reviewed.
Burnham, Jason P   +3 more
core   +2 more sources

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