Which Design and Biomaterial Factors Affect Clinical Wear Performance of Total Disc Replacements? A Systematic Review [PDF]
, 2014 Background Total disc replacement was clinically introduced to reduce pain and preserve segmental motion of the lumbar and cervical spine. Previous case studies have reported on the wear and adverse local tissue reactions around artificial prostheses ...
Alexander, Dominik D. +4 more
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An Evidence-Based Approach to Designing Virtual Patients [PDF]
, 2017 Virtual patients (VPs) are used for developing clinical reasoning which is an area of deficit in medical trainees. There are a number of studies showing that virtual patients have a positive effect on clinical reasoning skills but it remains uncertain ...
Collins, Benjamin
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Prebiotic, Probiotic, and Synbiotic Supplementation in Chronic Kidney Disease: A Systematic Review and Meta-analysis [PDF]
, 2019 Gut dysbiosis has been implicated in the pathogenesis of chronic kidney disease (CKD). Restoring gut microbiota with prebiotic, probiotic, and synbiotic supplementation has emerged as a potential therapeutic intervention but has not been systematically ...
Campbell, Katrina L. +3 more
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Combination Therapy Use and Associated Events in Clinical Practice Following Dissemination of Trial Findings: A De-Implementation Study Using Interrupted Time Series Analysis [PDF]
, 2023 Heather Campbell +3 more
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Health (including Clinical Studies) [PDF]
Politics, science, research and the public base their discussions on comprehensive, valid and systematic health care data. Data based information is needed in order to measure the results or success of a policy of procedure.
Bertram Häussler, Elke Hempel
core
Clinical Studies - Outcomes [PDF]
Clinical Chemistry and Laboratory Medicine (CCLM), 2021 openaire +2 more sources
The academic backbone: longitudinal continuities in educational achievement from secondary school and medical school to MRCP(UK) and the specialist register in UK medical students and doctors [PDF]
, 2013 Background: Selection of medical students in the UK is still largely based on prior academic achievement, although doubts have been expressed as to whether performance in earlier life is predictive of outcomes later in medical school or post-graduate ...
A Elder +55 more
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Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. [PDF]
, 2019 Mood disorders are highly prevalent and are the leading cause of disability worldwide. The neurobiological mechanisms underlying depression remain poorly understood, although theories regarding dysfunction within various neurotransmitter systems have ...
Dulawa, Stephanie C, Janowsky, David S
core
Transplantable melanomas in hamsters and gerbils as models for human melanoma : sensitization in melanoma radiotherapy : from animal models to clinical trials [PDF]
, 2018 The focus of the present review is to investigate the role of melanin in the radioprotection of melanoma and attempts to sensitize tumors to radiation by inhibiting melanogenesis. Early studies showed radical scavenging, oxygen consumption and adsorption
Andrzej Słominski +11 more
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Journal of Lipid Research, 2019 Fibroblast growth factor (FGF)19, an endocrine hormone produced in the gut, acts in the liver to control bile acid synthesis. NGM282, an engineered FGF19 analog, is currently in clinical development for treating nonalcoholic steatohepatitis. However, the
Mei Zhou +5 more
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