A CLINICAL STUDY OF MYOCARDITIS. [PDF]
It happens in every one's experience that at particular times clinical observation is specially rich in a single direction. So it has seemed to me that during the past year there have been under observation, both in hospital and private practice, a great number of cases in which the heart muscle seemed to be primarily at fault.
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Marketing and clinical trials : a case study [PDF]
Background: Publicly funded clinical trials require a substantial commitment of time and money. To ensure that sufficient numbers of patients are recruited it is essential that they address important questions in a rigorous manner and are managed well ...
Francis, D +54 more
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Case report: recurrent pituitary adenoma has increased load of somatic variants
Background Pituitary adenomas (PA) have an increased potential for relapse in one to 5 years after resection. In this study, we investigated the genetic differences in genomic DNA of primary and rapidly recurrent tumours in the same patient to explain ...
Raitis Peculis +13 more
doaj +1 more source
ON THE CLINICAL STUDY OF EPILEPSY. [PDF]
Read in the Section on Practice of Medicine and Materia Medica of the American Medical Association, May, 1884. Mr. Chairman:—When the eminent President of this Association, seconded by yourself, asked me to prepare some remarks for opening a discussion before the Section on Medicine, I felt that the desire was not so much that I should give a formal ...
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Pharmaceutical development of an amorphous solid dispersion formulation of elacridar hydrochloride for proof-of-concept clinical studies [PDF]
Objective: A novel tablet formulation containing an amorphous solid dispersion (ASD) of elacridar hydrochloride was developed with the purpose to resolve the drug’s low solubility in water and to conduct proof-of-concept clinical studies.
Schellens, J. H M +5 more
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Complementary feeding innovation from soybean flour and dragon fruit peel powder: An agricultural adaptation strategy to enhance hemoglobin and iron outcomes [PDF]
Malnutrition in early childhood is a contributor to stunting in Indonesia, with prevalence still above the WHO target. One key cause is the inadequacy of complementary feeding in providing sufficient micronutrients, especially iron, which is essential ...
Olivia Zora +4 more
doaj +1 more source
Extended-pulsed fidaxomicin versus vancomycin for Clostridium difficile infection in patients 60 years and older (EXTEND) : a randomised, controlled, open-label, phase 3b/4 trial [PDF]
Background Clostridium difficile infection causes severe complications and frequently recurs. An extended-pulsed fidaxomicin regimen might facilitate sustained clinical cure by prolonging C difficile suppression and supporting gut microbiota recovery. We
EXTEND Clinical Study Grp
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Medication Use and Clinical Outcomes by the Dutch Institute for Clinical Auditing Medicines Program: Quantitative Analysis [PDF]
BACKGROUND: The Dutch Institute for Clinical Auditing (DICA) Medicines Program was set up in September 2018 to evaluate expensive medicine use in daily practice in terms of real-world effectiveness using only existing data sources.
van Breeschoten, Jesper +11 more
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Background Most studies of risk factors for new low back pain (LBP) have been conducted in Western populations, but because of cultural and environmental differences, the impact of causal factors may not be the same in other countries.
Mika Kawaguchi +6 more
doaj +1 more source
Variability in adherence to clinical practice guidelines and recommendations in COPD outpatients: a multi-level, cross-sectional analysis of the EPOCONSUL study [PDF]
Background Clinical audits have reported considerable variability in COPD medical care and frequent inconsistencies with recommendations. The objectives of this study were to identify factors associated with a better adherence to clinical practice ...
López Campos, José Luis +31 more
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