Results 41 to 50 of about 41,914,794 (278)

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Randomized open-label non-inferiority trial of paracetamol or celecoxib for patients with chronic low back pain

Scientific Reports
Pharmacological treatment is commonly used for patients with chronic low back pain (CLBP). However, very low-quality evidence exists for paracetamol as a treatment option for CLBP; therefore, recommendations are contradictory among the guidelines.
Kazuhiro Hayashi, Kenji Miki, Hiroshi Ueno, Miho Sekiguchi, Young-Chang Arai, Takuya Nikaido, Yasuhiro Shiga, Masayuki Inoue, Hideki Kataoka, Yuya Kawarai, Yoshiyuki Kimura, Keisuke Shimizu, Kazuhiro Shimo, Yukiko Shiro, Katsuyoshi Tanaka, So Tanaka, Yoshiyuki Hirakawa, Kousei Miura, Masao Yukioka   +18 more
doaj   +1 more source

Ewing Sarcoma in Infants and Children Under 2 Years of Age: A French Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma, the second most common primary bone cancer in children, requires intensive treatment that may lead to significant long‐term sequelae, particularly in infants. We retrospectively analyzed data from 1621 French patients treated between 1988 and 2015 within the EW88/93/97 or EE99 trials, focusing on 17 infants diagnosed before 24 ...
Elodie Verdier, Nathalie Cozic, Marie‐Dominique Tabone, Gaelle Pierron, Perrine Marec‐Berard, Sarah Winter, Gabriel Revon‐Rivière, Cyril Lervat, Dominique Plantaz, Marie‐Pierre Castex, Gregory Guimard, Estelle Thebaud, Stephanie Proust, Laure Saumet, Natacha Entz‐Werle, Sophie Taque, Cécile Vérité, Marta Jimenez, Nathalie Gaspar   +18 more
wiley   +1 more source

Outcomes of 25-Gauge Vitrectomy for Tractional and Nontractional Diabetic Macular Edema with Proliferative Diabetic Retinopathy

Journal of Ophthalmology, 2019
The benefit of pars plana vitrectomy with internal limiting membrane peeling for tractional macular edema and diffuse nontractional macular edema in diabetic retinopathy has been reported.
Hideaki Someya, Kei Takayama, Masaru Takeuchi, Hiroshi Yokoyama, Takeshi Kimura, Masakazu Morioka, Yoshihiro Takamura, Seiji Sameshima, Tetsuo Ueda, Nahoko Ogata, Maki Tashiro, Shigehiko Kitano, Taiji Sakamoto   +12 more
doaj   +1 more source

Mixed-Thickness Tunnel Access (MiTT) through a Linear Vertical Mucosal Incision for a Minimally Invasive Approach for Root Coverage Procedures in Anterior and Posterior Sites: Technical Description and Case Series with 1-Year Follow-Up

Dentistry Journal, 2023
Purpose: The goal of this article was to introduce a new root coverage (RC) technique, the mixed-thickness tunnel access (MiTT) technique, which approaches a full-split design and intends to augment soft tissues coronal to the gingival margin.
Tiago Marques, Nuno Bernardo Malta dos Santos, Manuel Sousa, Juliana Campos Hasse Fernandes, Gustavo Vicentis Oliveira Fernandes   +4 more
doaj   +1 more source

Early clinical development of targeted anticancer agents [PDF]

, 2017
Van Brummelen studied the safety and preliminary signs of efficacy of several novel targeted anticancer agents in phase I trials. In her thesis, she reports the results of trials with the immunotherapies pembrolizumab and cergutuzumab-amunaleukin, and ...
van Brummelen, E.M.J., Pharmacoepidemiology and Clinical Pharmacology, Sub Clinical Pharmacology   +2 more
core  

Provider and Parent Perspectives on Prioritizing the “Asking and Monitoring” Pediatric Cancer Psychosocial Standards of Care

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families (“Standards”) are evidence‐based guidelines for psychosocial care in pediatric oncology. Care related to the three “Asking and Monitoring” Standards—Assessment of Psychosocial Needs, Assessment of Financial Needs, and Monitoring Neurocognitive Problems ...
Julia B. Tager, Natalie Koskela‐Staples, Emily M. Pariseau, Michele Scialla, Kimberly Buff, Lori Wiener, Victoria Sardi Brown, Anne E. Kazak, Kimberly S. Canter   +8 more
wiley   +1 more source

Characterization of the visually impaired patients with diabetes mellitus in Japan

Journal of Diabetes Investigation
Aims/Introduction To conduct a multicenter survey of visually impaired patients with diabetes mellitus (DM) and to identify the physical and ocular characteristics that lead to blindness in Japan.
Yuka Sugihara, Yoshihiro Takamura, Yutaka Yamada, Masakazu Morioka, Makoto Gozawa, Kumiko Kato, Takao Hirano, Fumiko Murao, Miho Shimizu, Sentaro Kusuhara, Tomoya Murakami, Yuki Takenaka, Naoko Okabe, Tatsuya Jujo, Hiroto Terasaki, Daisuke Nagasato, Zhenyu Dong, Shigeo Yoshida, Shuntaro Ogura, Kanako Yasuda, Gaku Ishigooka, Osamu Sawada, Fumiaki Higashijima, Masaru Inatani   +23 more
doaj   +1 more source

A CLINICAL STUDY OF VAGOTONIA [PDF]

Archives of Internal Medicine, 1913
In 1899 there appeared in the New York Medical Journal three admirable articles by Meltzer, 1 in which he deals with the function of inhibition. He speaks of the entire life of the animal as being a delicately adjusted equilibrium between excitation and inhibition and cites instances in which the slightest deviation of the resultant in the nervous ...
openaire   +2 more sources

Surgical Management of the Axilla in Clinically Node-Positive Breast Cancer Patients Converting to Clinical Node Negativity through Neoadjuvant Chemotherapy : Current Status, Knowledge Gaps, and Rationale for the EUBREAST-03 AXSANA Study [PDF]

, 2021
In the last two decades, surgical methods for axillary staging in breast cancer patients have become less extensive, and full axillary lymph node dissection (ALND) is confined to selected patients.
Geeta Kadayaprath, Dostalek, Lukas, Rubio, Isabel T., Cakmak, Guldeniz Karadeniz, Jean-Marc Classe, Niinikoski, Laura, Peter Paluchowski, Thorsten Kühn, Steffi Hartmann, Thill, Marc, Nina, Helidon, Kontos, Michalis, Marc Thill, Elmar Stickeler, Karadeniz Cakmak, Guldeniz, Bonci, Eduard-Alexandru, Pinto, David, Matrai, Zoltan, Kühn, Thorsten, Petr Krivorotko, Hartmann, Steffi, Oreste Gentilini, Michael Hauptmann, Dawid Murawa, Laura Niinikoski, Banys-Paluchowski, Maggie, Paluchowski, Peter, Kadayaprath, Geeta, Isabel Rubio, Helidon Nina, Jens-Uwe Blohmer, de Boniface, Jana, Classe, Jean-Marc, Rosa Di Micco, Maggie Banys-Paluchowski, Hauptmann, Michael, Krivorotko, Petr, Gasparri, Maria Luisa, Di Micco, Rosa, Eduard-Alexandru Bonci, Peintinger, Florentia, Guldeniz Karadeniz Cakmak, the AXSANA Study Group, Appelgren, Matilda, Ellen Schlichting, Solbach, Christine, Maria Gasparri, Blohmer, Jens-Uwe, Michalis Kontos, Matilda Appelgren, Jana de Boniface, Zoltan Matrai, Florentia Peintinger, Lukas Dostalek, David Pinto, Christine Solbach, Schlichting, Ellen, Stickeler, Elmar, Gentilini, Oreste, Murawa, Dawid   +59 more
core   +1 more source