Results 51 to 60 of about 12,182,221 (303)

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Randomized open-label non-inferiority trial of paracetamol or celecoxib for patients with chronic low back pain

Scientific Reports
Pharmacological treatment is commonly used for patients with chronic low back pain (CLBP). However, very low-quality evidence exists for paracetamol as a treatment option for CLBP; therefore, recommendations are contradictory among the guidelines.
Kazuhiro Hayashi, Kenji Miki, Hiroshi Ueno, Miho Sekiguchi, Young-Chang Arai, Takuya Nikaido, Yasuhiro Shiga, Masayuki Inoue, Hideki Kataoka, Yuya Kawarai, Yoshiyuki Kimura, Keisuke Shimizu, Kazuhiro Shimo, Yukiko Shiro, Katsuyoshi Tanaka, So Tanaka, Yoshiyuki Hirakawa, Kousei Miura, Masao Yukioka   +18 more
doaj   +1 more source

Delivering a “Dose of Hope”: A Faith-Based Program to Increase Older African Americans’ Participation in Clinical Trials [PDF]

, 2015
Background: Underrepresentation of older-age racial and ethnic minorities in clinical research is a significant barrier to health in the United States, as it impedes medical research advancement of effective preventive and therapeutic strategies ...
Anderson, Aaron M., Archibald, Matthew, Boggavarapu, Sahithi, Bolton, Marcus, Braxton, Nikia, Fenimore, Vincent L., Frew, Paula M., Horton, Takeia, Kalokhe, Ameeta S., Omer, Saad B., Owens, Lauren, Parker, Kimberly, Root, Christin M., Saint-Victor, Diane, Schamel, Jay, Shapiro, Eve   +15 more
core   +3 more sources

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Outcomes of 25-Gauge Vitrectomy for Tractional and Nontractional Diabetic Macular Edema with Proliferative Diabetic Retinopathy

Journal of Ophthalmology, 2019
The benefit of pars plana vitrectomy with internal limiting membrane peeling for tractional macular edema and diffuse nontractional macular edema in diabetic retinopathy has been reported.
Hideaki Someya, Kei Takayama, Masaru Takeuchi, Hiroshi Yokoyama, Takeshi Kimura, Masakazu Morioka, Yoshihiro Takamura, Seiji Sameshima, Tetsuo Ueda, Nahoko Ogata, Maki Tashiro, Shigehiko Kitano, Taiji Sakamoto   +12 more
doaj   +1 more source

Mixed-Thickness Tunnel Access (MiTT) through a Linear Vertical Mucosal Incision for a Minimally Invasive Approach for Root Coverage Procedures in Anterior and Posterior Sites: Technical Description and Case Series with 1-Year Follow-Up

Dentistry Journal, 2023
Purpose: The goal of this article was to introduce a new root coverage (RC) technique, the mixed-thickness tunnel access (MiTT) technique, which approaches a full-split design and intends to augment soft tissues coronal to the gingival margin.
Tiago Marques, Nuno Bernardo Malta dos Santos, Manuel Sousa, Juliana Campos Hasse Fernandes, Gustavo Vicentis Oliveira Fernandes   +4 more
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Characterization of the visually impaired patients with diabetes mellitus in Japan

Journal of Diabetes Investigation
Aims/Introduction To conduct a multicenter survey of visually impaired patients with diabetes mellitus (DM) and to identify the physical and ocular characteristics that lead to blindness in Japan.
Yuka Sugihara, Yoshihiro Takamura, Yutaka Yamada, Masakazu Morioka, Makoto Gozawa, Kumiko Kato, Takao Hirano, Fumiko Murao, Miho Shimizu, Sentaro Kusuhara, Tomoya Murakami, Yuki Takenaka, Naoko Okabe, Tatsuya Jujo, Hiroto Terasaki, Daisuke Nagasato, Zhenyu Dong, Shigeo Yoshida, Shuntaro Ogura, Kanako Yasuda, Gaku Ishigooka, Osamu Sawada, Fumiaki Higashijima, Masaru Inatani   +23 more
doaj   +1 more source

Distributed Queries for Quality Control Checks in Clinical Trials [PDF]

, 2011
Operational Quality Control (QC) checks are standard practice in clinical trials and ensure ongoing compliance with the study protocol, standard operating procedures (SOPs) and Good Clinical Practice (GCP).
Brinkley, James F, Detwiler, Landon T, Franklin, Joshua D, Nichols, Nolan   +3 more
core   +1 more source

Prevalence of asthma and COPD and blood eosinophil count in a middle-aged Belgian population [PDF]

, 2019
Various phenotypes exist in asthma and Chronic Obstructive Pulmonary Disease (COPD). These are important to identify in order to guide treatment decisions.
Brusselle, Guy, De Buyzere, Marc, Lahousse, Lies, Rietzschel, Ernst, Wijnant, Sara   +4 more
core   +1 more source