Results 81 to 90 of about 41,914,794 (278)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Ganoderma lucidum: a comprehensive review of phytochemistry, efficacy, safety and clinical study

open access: yesFood Science and Human Wellness
Ganoderma lucidum, one of the most well-known edible fungi, is believed to be very benef icial for longevity and vitality. A long usage history suggests that G. lucidum has various clinical therapeutic effects.
Sijia Wu   +7 more
doaj   +1 more source

Innovative Strategies of Reprogramming Immune System Cells by Targeting CRISPR/Cas9-Based Genome-Editing Tools: A New Era of Cancer Management

open access: yesInternational Journal of Nanomedicine, 2023
Khaled S Allemailem,1 Mohammed A Alsahli,1 Ahmad Almatroudi,1 Faris Alrumaihi,1 Waleed Al Abdulmonem,2 Amira A Moawad,3 Wanian M Alwanian,1 Nahlah Makki Almansour,4 Arshad Husain Rahmani,1 Amjad Ali Khan5 1Department of Medical Laboratories, College of ...
Allemailem KS   +9 more
doaj  

GPla Polymorphisms Are Associated with Outcomes in Patients at High Cardiovascular Risk

open access: yesFrontiers in Cardiovascular Medicine, 2017
BackgroundPlatelet membrane glycoprotein receptors mediate thrombus formation. GP Ia/IIa is an essential platelet integrin receptor. Single-nucleotide polymorphisms (SNPs) of the GP Ia/IIa gene alter GP Ia/IIa expression; however, their influence on ...
Dominik Rath   +15 more
doaj   +1 more source

Pharmaceutical development of an amorphous solid dispersion formulation of elacridar hydrochloride for proof-of-concept clinical studies [PDF]

open access: yes, 2017
Objective: A novel tablet formulation containing an amorphous solid dispersion (ASD) of elacridar hydrochloride was developed with the purpose to resolve the drug’s low solubility in water and to conduct proof-of-concept clinical studies.
Schellens, J. H M   +5 more
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A clinical case of diffuse odontogenic facial phlegmon

open access: yesPatologìâ
The aim of the work is to describe and discuss an unusual clinical case of diffuse facial phlegmon in order to increase the awareness and competence of clinicians who may encounter similar cases. Materials and methods.
A. S. Varzhapetian, O. O. Kokar
doaj   +1 more source

脑血管病临床医师科研能力的培养 Cultivation of Scientific Research Ability of Cerebrovascular Disease Clinicians

open access: yesZhongguo cuzhong zazhi, 2019
临床研究是现代循证医学的基础,临床医师是临床研究的主要参与者,因此临床医师科 研素养和能力的培养对于临床试验的规范和医学科研的进步意义重大。本文主要探讨了临床研究医 师培养的必要性,明确临床研究能力的培养目标,积极探索临床研究能力的培养途径。通过培养医 师临床研究能力推动脑血管病事业持续发展。 Abstract: Clinical studies are the base of modern evidence-based medicine (EBM), and clinicians are ...
叶玉梅,陈瑛,许蓉,任依
doaj   +1 more source

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