Establishing a Successful Clinical Research Program [PDF]
Clinical research (CR) is a natural corollary to clinical surgery. It gives an investigator the opportunity to critically review their results and develop new strategies. This article covers the critical factors and the important components of a successful CR program.
Daniele, Scoglio, Alessandro, Fichera
openaire +2 more sources
Enterococcal periprosthetic joint infection: clinical and microbiological findings from an 8-year retrospective cohort study [PDF]
BACKGROUND: Treatment of enterococcal periprosthetic joint infections (PJI) is challenging due to non-standardized management strategies and lack of biofilm-active antibiotics. The optimal surgical and antimicrobial therapy are unknown.
Akgün, Doruk +4 more
core +1 more source
Oxidative stress and the use of antioxidants in stroke [PDF]
Transient or permanent interruption of cerebral blood flow by occlusion of a cerebral artery gives rise to an ischaemic stroke leading to irreversible damage or dysfunction to the cells within the affected tissue along with permanent or reversible ...
Ord, Emily N.J. +2 more
core +4 more sources
Efficacy and Safety of Uterine Artery Embolisation for Postpartum Haemorrhage: A Systematic Review and Meta-analysis [PDF]
Introduction: Postpartum Haemorrhage (PPH) is one of the main causes of maternal morbidity and mortality globally, accounting for about 25% of maternal deaths.
RAHUL ARKAR +3 more
doaj +1 more source
Outcome of secondary root canal treatment: a systematic review of the literature.
UNLABELLED: AIMS (I): To investigate the effects of study characteristics on the reported success rates of secondary root canal treatment (2 degrees RCT or root canal retreatment); and (ii) to investigate the effects of clinical factors on the success of
Gulabivala, K, Mann, V, Ng, Y-L
core +1 more source
Acute Stroke Multimodal Imaging: Present and Potential Applications toward Advancing Care. [PDF]
In the past few decades, the field of acute ischemic stroke (AIS) has experienced significant advances in clinical practice. A core driver of this success has been the utilization of acute stroke imaging with an increasing focus on advanced methods ...
Liang, John W. +3 more
core +2 more sources
Retaining the Next Generation of Nurses: The Wisconsin Nurse Residency Program Provides a Continuum of Support [PDF]
Because of the high costs associated with new graduate nurse turnover, an academic-service partnership developed a nurse residency program that provides a comprehensive support system that spans 15 months.
Alspach +9 more
core +2 more sources
ObjectivesTo assess differences in 24-month oncologic and functional outcomes in men with low to intermediate-risk prostate cancer treated with MRI-guided transurethral ultrasound ablation (TULSA) using intentionally conservative versus intensified ...
Gencay Hatiboglu +10 more
doaj +1 more source
The GUIDES checklist: development of a tool to improve the successful use of guideline-based computerised clinical decision support [PDF]
Background: Computerised decision support (CDS) based on trustworthy clinical guidelines is a key component of a learning healthcare system. Research shows that the effectiveness of CDS is mixed.
Aertgeerts, Bert +7 more
core +6 more sources
Selective Brain Hypothermia in Acute Ischemic Stroke: Reperfusion Without Reperfusion Injury
In acute ischemic stroke, early recanalization of the occluded artery is crucial for best outcome to be achieved. Recanalization aims at restoring blood flow to the ischemic tissue (reperfusion) and is achieved with pharmacological thrombolytic drugs ...
Jae H. Choi +8 more
doaj +1 more source

