Results 51 to 60 of about 7,995,840 (309)

Performance and outcomes of transvenous rotational lead extraction: Results from a prospective, monitored, international clinical study

Heart Rhythm O2, 2021
Background: Transvenous lead extraction (TLE) plays a critical role in managing patients with cardiovascular implantable electronic devices. Mechanical TLE tools, including rotational sheaths, are used to overcome fibrosis and calcification surrounding ...
Saumya Sharma, MD, Byron K. Lee, MD, FACC, Anuj Garg, MD, Robert Peyton, MD, Brian T. Schuler, MD, Pamela Mason, MD, FHRS, FACC, Peter Paul Delnoy, MD, PhD, Mark M. Gallagher, BSc, MD, FRCPI, Ramesh Hariharan, MD, Raymond Schaerf, MD, FHRS, Ruirui Du, MS, Nina D. Serratore, PhD, Christoph T. Starck, MD, PhD, FEHRA   +12 more
doaj   +1 more source

Establishing a Successful Clinical Research Program [PDF]

Clinics in Colon and Rectal Surgery, 2014
Clinical research (CR) is a natural corollary to clinical surgery. It gives an investigator the opportunity to critically review their results and develop new strategies. This article covers the critical factors and the important components of a successful CR program.
Daniele, Scoglio, Alessandro, Fichera
openaire   +2 more sources

Success in Neoliberal Capitalist Societies [PDF]

, 2019
Main research document, 22 pages. Presentation outline, 5 pages. Link to the Prezi presentation can be found in prezi_link_leonard_urs_2019 .Success, particularly in our society in the US, is a complex social construct that often determines the life an ...
Leonard, Frankie
core  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Ceftazidime–Avibactam in Multidrug-Resistant Klebsiella spp. Infections: Is Monotherapy as Effective as Combination Therapy?

Antibiotics
Background/Objectives: Carbapenem-resistant Klebsiella spp. (CRK) causes healthcare-associated infections with high mortality. This study evaluated the clinical outcomes of ceftazidime–avibactam (CZA) therapy in CRK infections.
Rukiyye Bulut, İbrahim Erayman, Bahar Kandemir, Pınar Belviranlı Keskin   +3 more
doaj   +1 more source

Recent Clinical Successes in Liposomal Nanomedicines

International Journal of Drug Discovery and Pharmacology, 2023
Review Recent Clinical Successes in Liposomal Nanomedicines Wenjie Gu , Gavin P. Andrews , and Yiwei Tian , * School of Pharmacy, Queen’s University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK. * Correspondence: y.tian@qub.ac.uk     Received: 19 December 2022 Accepted: 26 January 2023 Published: 3 February 2023   Abstract: The intrinsic ...
Gu, Wenjie, Andrews, Gavin P., Tian, Yiwei   +2 more
openaire   +3 more sources

Clinical experience, performance in final examinations, and learning style in medical students: prospective study [PDF]

, 1998
Objective: To assess whether the clinical experience of undergraduate medical students relates to their performance in final examinations and whether learning styles relate either to final examination performance or to the extent of clinical experience.
Richards, P., I C McManus, B C Winder, Sproston, K.A., K A Sproston, McManus, I.C., Winder, B.C., P Richards   +7 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Clinical success rate of fissure sealants: One-year follow-up

European Oral Research, 2020
Purpose The aim of this study is to evaluate clinical success rate of resin-based fissure sealants applied at Istanbul University, Department of Pediatric Dentistry after 1 year of application.Materials and Methods Children with at least one pair of ...
Mine Koruyucu, Dilara Bektaş, Cengiz Aydınoğlu, Pelin Barlak, Figen Seymen   +4 more
doaj   +1 more source