Results 41 to 50 of about 972,967 (262)
AntibioticsIntroduction: Infections attributed to multidrug-resistant organisms have resulted in a significant clinical burden, high mortality, and excessive costs.
Ryan K. Shields +7 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
AntibioticsBackground/Objectives: Carbapenem-resistant Klebsiella spp. (CRK) causes healthcare-associated infections with high mortality. This study evaluated the clinical outcomes of ceftazidime–avibactam (CZA) therapy in CRK infections.
Rukiyye Bulut +3 more
doaj +1 more source
Three Decades of Success for Clinical Neuroradiology [PDF]
Clinical Neuroradiology, 2021 No abstract available.
openaire +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Clinical success rate of fissure sealants: One-year follow-up
European Oral Research, 2020 Purpose The aim of this study is to evaluate clinical success rate of resin-based fissure sealants applied at Istanbul University, Department of Pediatric Dentistry after 1 year of application.Materials and Methods Children with at least one pair of ...
Mine Koruyucu +4 more
doaj +1 more source
Recent Clinical Successes in Liposomal Nanomedicines
International Journal of Drug Discovery and Pharmacology, 2023 Review Recent Clinical Successes in Liposomal Nanomedicines Wenjie Gu , Gavin P. Andrews , and Yiwei Tian , * School of Pharmacy, Queen’s University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK. * Correspondence: y.tian@qub.ac.uk Received: 19 December 2022 Accepted: 26 January 2023 Published: 3 February 2023 Abstract: The intrinsic ...
Gu, Wenjie +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Gynecology Obstetrics & Reproductive Medicine, 2018 Objective: We aimed to assess the effect of serum albumin level adjusted progesterone levels on the trigger day on clinical pregnancy rate in ICSI cycles.
Cigdem Yayla Abide +5 more
doaj +1 more source