CD28 between tolerance and autoimmunity: The side effects of animal models [version 1; referees: 2 approved] [PDF]
Regulation of immune responses is critical for ensuring pathogen clearance and for preventing reaction against self-antigens. Failure or breakdown of immunological tolerance results in autoimmunity.
A Aruffo +57 more
core +2 more sources
Applying thematic synthesis to interpretation and commentary in epidemiological studies: identifying what contributes to successful interventions to promote hand hygiene in patient care [PDF]
Objectives: Hand hygiene is considered the most important preventive measure for healthcare associated infections, but adherence is suboptimal. We previously undertook a Cochrane Review which demonstrated that interventions to improve adherence are ...
Birgand +9 more
core +2 more sources
Process Improvement for Maximized Therapeutic Innovation Outcome. [PDF]
Deconvoluting key biological mechanisms forms the framework for therapeutic discovery. Strategies that enable effective translation of those insights along the development and regulatory path ultimately drive validated clinical application in patients ...
Terzic, Andre, Waldman, Scott A.
core +2 more sources
Clinical Insights Into Hypercalcemia of Malignancy in Childhood
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source
Objectives This clinical report aims to highlight the factors affecting the clinical success of alveolar ridge mini-implants used for orthodontic anchorage and provide an overview of the biomechanical versatility of this miniscrew and steps involving the
Sarah Abu Arqub +6 more
doaj +1 more source
Community Clinical Pastoral Training -- A Success for Ecumenism in Shreveport [PDF]
A review of the seven years\u27 activity of the Shreveport Medical Society\u27s committee of Medicine & Religion which lead to the formation of the Clinical Pastoral Training Program, is presented by the co-chairmen of the ...
Black, Charles L., Holoubek, Joe E.
core +1 more source
MRSA eradication of newly acquired lower respiratory tract infection in cystic fibrosis [PDF]
UK cystic fibrosis (CF) guidelines recommend eradication of methicillin-resistant Staphylococcus aureus (MRSA) when cultured from respiratory samples.
Downey, DG +7 more
core +3 more sources
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman +8 more
wiley +1 more source
A foot drop compensation device based on surface multi-field functional electrical stimulation—Usability study in a clinical environment [PDF]
Functional electrical stimulation applies electrical pulses to the peripheral nerves to artificially achieve a sensory/motor function. When applied for the compensation of foot drop it provides both assistive and therapeutic effects.
Asiain-Aristu, Jose Ramón +6 more
core +2 more sources
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian +7 more
wiley +1 more source

