Results 71 to 80 of about 7,995,840 (309)
Assessment of blinding success among dental implant clinical trials: A systematic review
Dental Hypotheses, 2015 Introduction: It is widely believed that blinding is a cornerstone of randomized clinical trials and that significant bias may result from unsuccessful blinding.
Jafar Kolahi, Saber Khazaei
doaj +1 more source
, 2018 The purpose of this systematic review was to identify and evaluate economic evidence to inform the clinical recommendations of this NCG. Review of the cost-effectiveness of health technologies enables guideline developers to explicitly consider how ...
HRB-CICER (Collaboration in Ireland for Clinical Effectiveness Reviews)
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Exploring MBA career success [PDF]
, 2006 Purpose – The purpose of this paper is to examine the meaning of career success in relation to the attainment of an MBA degree, for a group of experienced managers.
Hay, AJ, Hodgkinson, M
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ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Endoscopy International OpenBackground and Study Aim We aimed to identify factors associated with clinical success after endoscopic treatment of gastrointestinal transmural defects and to develop an exploratory internally validated prediction model.
Irene Navarrete-Pérez +9 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
The Pharmacological Management of Cancer Pain in Adults Clinical Audit Tool
, 2016 The audit standards are based on the Pharmacological Management of Cancer Pain in Adults NCEC National Clinical Guideline No. 9. In developing this tool consideration has been given to the clinical issues covered by the guideline and the potential ...
National Clinical Programme for Palliative Care
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Challenges in the clinical development of orphan drugs [PDF]
, 2015 Rare diseases are characterised by a low prevalence. There are so many different rare diseases, that millions of people are affected.The vast majority of these diseases suffer from a lack of approved treatment options and orphan drugs (ODs) therefore ...
Pharmacoepidemiology and Clinical Pharmacology +2 more
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Pharmaceutical development of an amorphous solid dispersion formulation of elacridar hydrochloride for proof-of-concept clinical studies [PDF]
, 2017 Objective: A novel tablet formulation containing an amorphous solid dispersion (ASD) of elacridar hydrochloride was developed with the purpose to resolve the drug’s low solubility in water and to conduct proof-of-concept clinical studies.
Schellens, J. H M +5 more
core +2 more sources
, 2023 Objective The purpose of this double-blind and split-mouth randomized controlled clinical trial was to evaluate the clinical success of the placement technique (bulk-filling and incremental techniques) of a bulk-fill resin composite in Class II carious ...
DEMİRBUĞA, SEZER +1 more
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