Results 181 to 190 of about 3,635,661 (309)

Insights into the adoption of innovative clinical trials across therapeutic areas using clinical trials registry data and large Language models. [PDF]

Sci Rep
Azzolina D, Scisciola V, Vedovelli L, Iervolino D, Khan MR, Comoretto RI, Murri MB, Gregori D.   +7 more
europepmc   +1 more source

Ocular and Corneal Aberrations changes in controlled randomized clinical trial MiSight® Assessment Study Spain (MASS) [PDF]

, 2020
Daniela Lopes-Ferreira, Alicia Ruiz‐Pomeda, Belén Pérez-Sánchez, António Queirós, César Villa Collar   +4 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Multidisciplinary Perspectives of Clinical Trials in Theranostics. [PDF]

World J Nucl Med
Pathmaraj K, Lee ST.
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Enhancing randomized clinical trials with digital twins. [PDF]

NPJ Syst Biol Appl
Akbarialiabad H, Pasdar A, Murrell DF, Mostafavi M, Shakil F, Safaee E, Leachman SA, Haghighi A, Tarbox M, Bunick CG, Grada A.   +10 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Artificial Intelligence and the future of clinical trials. [PDF]

Contemp Clin Trials Commun
Sergi CM, Sesso HD.
europepmc   +1 more source

Clinical effectiveness/child-patient and parent satisfaction of two topical fluoride treatments for caries: a randomised clinical trial [PDF]

Ilze Maldupa, Nicola Innes, Ilona Viduskalne, Anda Brinkmane, Egita Senakola, Karina Krumina, Sergio Uribe   +6 more
openalex   +1 more source

Comment on “Low-level laser therapy with 940 nm diode laser on stability of dental implants: a randomized controlled clinical trial” [PDF]

, 2017
Rodrigo Duarte Farias
openalex   +1 more source