Results 231 to 240 of about 14,066,519 (402)

Conventional quality-of-life data analyses underestimate gains in Mantle Cell Lymphoma clinical trials: A re-examination of enrich study data [PDF]

open access: bronze
Jeremy Hobart   +19 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

The status quo of the development of decentralized clinical trials. [PDF]

open access: yesFront Med (Lausanne)
Chen X   +7 more
europepmc   +1 more source

Clinical Trials Registration

open access: yesPLoS Medicine, 2006
Rockhold, Frank W, Krall, Ronald L
openaire   +3 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

An assessment of the informativeness of clinical trials in digital mental health. [PDF]

open access: yesNpj Ment Health Res
O'Dea B   +6 more
europepmc   +1 more source

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