Results 101 to 110 of about 624,126 (316)

Traditional Chinese Medicine and Its Role in Women’s Health [PDF]

open access: yes, 2020
This paper is a literature review of traditional Chinese medicine and its role in women’s health. A search was performed and a group of 208 articles were initially found using the Liberty Summons search engine.
Smith, Ezekiel
core   +1 more source

Addressing social issues in a universal HIV test and treat intervention trial (ANRS 12249 TasP) in South Africa: methods for appraisal [PDF]

open access: yes, 2015
Background: The Universal HIV Test and Treat (UTT) strategy represents a challenge for science, but is also a challenge for individuals and societies.
AK Rowe   +65 more
core   +7 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Position Paper on Road Map for RNA Virus Research in India

open access: yesFrontiers in Microbiology, 2018
The Indian subcontinent with its population density, climatic conditions, means of subsistence, socioeconomic factors as well as travel and tourism presents a fertile ground for thriving of RNA viruses. Despite being pathogens of huge significance, there
Guruprasad R. Medigeshi   +2 more
doaj   +1 more source

Written information about individual medicines for consumers.

open access: yes, 2009
Medicines are the most common intervention in most health services. As with all treatments, those taking medicines need sufficient information: to enable them to take and use the medicines effectively, to understand the potential harms and benefits, and ...
Al-Eidan   +186 more
core   +1 more source

Systemic corticosteroids for acute otitis media in children [PDF]

open access: yes, 2018
Background: Acute otitis media (AOM) is a common acute infection in children. Pain is its most prominent and distressing symptom. Antibiotics are commonly prescribed for AOM, although they have only a modest effect in reducing pain at two to three days.
Beller, Elaine M   +6 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Study designs: Part 5 – interventional studies (II)

open access: yesPerspectives in Clinical Research, 2019
In the fifth piece of this series on research study designs, we continue the discussion on interventional studies (clinical trials), in which the investigator decides whether or not a particular participant receives the exposure (or intervention).
Rakesh Aggarwal, Priya Ranganathan
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A new cognitive evaluation battery for Down syndrome and its relevance for clinical trials

open access: yesFrontiers in Psychology, 2015
The recent prospect of pharmaceutical interventions for cognitive impairment of Down syndrome(DS) has boosted a number of clinical trials in this population.
Susana ede Sola   +28 more
doaj   +1 more source

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