Results 121 to 130 of about 635,069 (409)

Methodological and statistical topics in randomized controlled clinical trials [PDF]

, 1999
Escosteguy Claudia Caminha
openalex   +3 more sources

Insights From Pre-Clinical and Clinical Studies on the Role of Innate Inflammation in Atherosclerosis Regression

Frontiers in Cardiovascular Medicine, 2018
Atherosclerosis, the underlying cause of coronary artery (CAD) and other cardiovascular diseases, is initiated by macrophage-mediated immune responses to lipoprotein and cholesterol accumulation in artery walls, which result in the formation of plaques ...
Karishma Rahman, Edward A. Fisher
doaj   +1 more source

Lessons learned from two randomized controlled trials: CITIES and STOP-DKD

Contemporary Clinical Trials Communications, 2020
Background: Even well-designed, theoretically driven clinical trials can fall short of achieving the desired clinical outcomes. Our research team had an opportunity to conduct two randomized controlled trials that were enrolling patients in parallel ...
Leah L. Zullig, Megan M. Oakes, Felicia McCant, Hayden B. Bosworth   +3 more
doaj   +1 more source

Health topics emerged from brief‐motivational interviewing: A randomized clinical trial [PDF]

, 2023
Michelle C Arnett, Danna R Paulson, Michael D. Evans, Christine M. Blue, Yvette G Reibel   +4 more
openalex   +1 more source

Chloroprocaine 3% Gel as a Novel Ocular Topical Anesthetic: Results from a Multicenter, Randomized Clinical Trial in Patients Undergoing Cataract Surgery

Journal of Ocular Pharmacology and Therapeutics
Purpose: To compare the efficacy and safety of a novel ophthalmic anesthetic, chloroprocaine 3% gel to tetracaine 0.5% eye drops in patients undergoing cataract surgery with phacoemulsification. Methods: This was a prospective, randomized, multicenter, active-controlled, masked-observer, parallel group competitive equivalence study. The study comprised
Michele Figus, Fabrizio Giansanti, Edoardo Villani, Jorge L. Alió, Ladislav Jančo, Stefano Mercuri, Stefano Camnasio, Carlo Cagini   +7 more
openaire   +4 more sources

Culture-specific programs for children and adults from minority groups who have asthma (Review) [PDF]

, 2009
Background People with asthma who come from minority groups have poorer asthma outcomes and more asthma related visits to Emergency Departments (ED). Various programmes are used to educate and empower people with asthma and these have previously been ...
Bailey, EJ, Brown, N, Cates, CJ, Chang, AB, Kruske, SG, Morris, PS   +5 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

A new cognitive evaluation battery for Down syndrome and its relevance for clinical trials

Frontiers in Psychology, 2015
The recent prospect of pharmaceutical interventions for cognitive impairment of Down syndrome(DS) has boosted a number of clinical trials in this population.
Susana ede Sola, Susana ede Sola, Rafael ede la Torre, Rafael ede la Torre, Rafael ede la Torre, Gonzalo eSanchez-Benavides, Gonzalo eSanchez-Benavides, Bessy eBenejam, Aida eCuenca-Royo, Aida eCuenca-Royo, Laura edel Hoyo, Joan eRodriguez, Silvina eCatuara-Solarz, Judit eSanchez-Gutiérrez, Ivan eDueñas-Espin, Ivan eDueñas-Espin, Gimena eHernandez, Gimena eHernandez, Jordi ePeña-Casanova, Jordi ePeña-Casanova, Klaus eLangohr, Klaus eLangohr, Sebastià eVidela, Henri eBléhaut, Magi eFarré, Magi eFarré, Mara eDierssen, Mara eDierssen, the eTESDAD Study Group   +28 more
doaj   +1 more source

Does soy protein supplementation affect body composition in healthy exerciser adults? A systematic review and meta-analysis of clinical trials [PDF]

, 2019
Background objectives: The effects of soy protein supplementation on anthropometric parameters and body composition indices of healthy adults is equivocal.
Asbaghi, O., Clark, C.C.T., Falahi, E., Jafarnejad, S., Khosroshahi, M.Z., Rad, E.Y., Saboori, S.   +6 more
core   +3 more sources