Results 171 to 180 of about 55,609,055 (315)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

The Temple University Hospital EEG Data Corpus

Frontiers in Neuroscience, 2016
Iyad eObeid, Joseph ePicone
doaj   +1 more source

Editorial: Women in science-precision medicine 2023. [PDF]

Front Med (Lausanne)
O'Sullivan Coyne GH, Chen AP.
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Basket and umbrella trials in pediatric precision medicine: a systematic review of designs, opportunities, and challenges. [PDF]

BMC Med Res Methodol
Khan MR, Stendardo M, Bressan S, Vedovelli L, Berchialla P, Baldi I, Gregori D, Azzolina D.   +7 more
europepmc   +1 more source

The views of patients and healthy volunteers on participation in clinical trials: an exploratory survey study.

, 2012
BACKGROUND AND AIMS: This study was conducted to investigate the views of patients and healthy volunteers on participation in clinical trials. METHODS: A total of 291 clinical trial participants, including 140 patients and 151 healthy volunteers, were ...
추상희, 박경수, 박민수, 심재용   +3 more
core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Editorial: A holistic approach to oral-systemic health care: integrating natural and modern therapies. [PDF]

Front Dent Med
Taba M, Abidi AH, Chandrasekaran K.
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Editorial: Exerscience: exploring physical activity's role in diabetes and its complications. [PDF]

Front Endocrinol (Lausanne)
Qiu S, Parr EB, Wu T.
europepmc   +1 more source