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Reproducibility of Clinical Trials of Topical Glucocorticosteroids

International Journal of Dermatology, 1983
ABSTRACT:Clinical trials of topical glucocorticosteroids employ a variety of evaluating methods. This makes it difficult to assess the relative strengths of the products without resorting to direct comparative trials between them. We propose a standardized evaluation system for this class of pharmaceuticals that can easily be adopted by any competent ...
T, Fredriksson, A, Lassus, L, Salde
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Timely Topics in Statistical Methods for Clinical Trials

Annual Review of Biophysics and Bioengineering, 1982
Clinical trials provide information on the absolute and relative efficacy and side effects of medical treatments. These studies range from the well-designed, randomized controlled trial to a study of a single treat­ ment on a series of patients compared to the responses of previous patients treated another way.
T A, Louis, F, Mosteller, B, McPeek
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Clinical Trial of Topical Erythromycin in Inflammatory Acne

Drug Intelligence & Clinical Pharmacy, 1981
Sixty-nine informed subjects participated in a split-face, double-blind trial of topical erythromycin base 2% in Vehicle/N® versus Vehicle/N® alone. All subjects had grades II or III acne as described by Pillsbury. Study solutions were assigned to a randomly selected side of the subject's face. Solutions were applied twice daily.
R A, Prince   +3 more
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Clinical Trial of Topical Disodium Chromoglycate in Vernal Keratoconjunctivitis

Ophthalmologica, 2010
The clinical picture of Spring catarrh was studied in 96 cases. The duration of the disease was found to be 3.5 +/- 2.6 years. It exists all the year round with a higher frequency between April and August. Male children were affected about three times more frequently than females. The effect of DSCG was studied in 20 cases.
F, Sayegh, S, Samerra'e, M, Khateeb
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Influence of the Base on the Results of Clinical Trials with Topical Corticosteroids

Dermatologica, 2009
A comparative trial between betamethasone valerate and halcinonide has shown the former to be superior, thus contradicting the results from other trials. It is thought that the discrepancy is due to differences in the nature of the preparations used in the various studies.
D I, Vollum, C G, Sparkes
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Topical metformin in the treatment of melasma: A preliminary clinical trial

Journal of Cosmetic Dermatology, 2019
AbstractBackgroundMelasma is a common acquired pigmentary disorder characterized by symmetric hyperpigmented macules on the face. Triple combination cream (TCC) remains the gold standard treatment but its prolonged use often causes adverse effects. Recently, studies have shown that topical metformin has melanopenic action.AimsTo evaluate the safety and
Ravikumar Banavase Channakeshavaiah   +1 more
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Risks of Unoccluded Topical Steroids in Clinical Trials

Archives of Dermatology, 1980
Data were reviewed on the beneficial responses and adverse reactions among 2,849 patients in 14 paired-comparison studies with eight unoccluded topical corticosteroids in six steroid-responsive dermatoses. Adverse reactions were found to be mild, transient, and, for the most part, rare.
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Effect of Topical Garlic on Wound Healing and Scarring: A Clinical Trial

Dermatologic Surgery, 2020
BACKGROUND Historically, garlic containing compounds have been used on wounds to improve healing and ward off infection. Researchers have tested many of these ancient ointments, discovering that garlic is a common ingredient in those that are effective.
Minhal, Alhashim, Jamie, Lombardo
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