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Topical minocycline microspheres versus topical chlorhexidine gel as an adjunct to mechanical debridement of incipient peri‐implant infections: a randomized clinical trial

Journal of Clinical Periodontology, 2006
AbstractAim: This randomized clinical trial presents a 12‐month follow‐up of the clinical and microbiological results after application of minocycline microspheres as an adjunct to mechanical treatment of incipient peri‐implant infections compared with an adjunctive treatment using 1% chlorhexidine gel application.Material and Methods: Thirty‐two ...
Stefan, Renvert   +4 more
openaire   +2 more sources

Efficacy and safety of calcipotriol as a potential topical treatment of acne vulgaris: a randomized, controlled, triple blinded, split-face clinical trial

Clinical and Experimental Dermatology, 2023
Abstract Background Acne vulgaris is a common skin problem that may result in significant scarring and systemic comorbidities. Adverse effects and increasing resistance to available treatments urge the development of new therapeutics.
Ayman Mahran   +3 more
openaire   +2 more sources

Selective laser trabeculoplasty versus topical medication as initial glaucoma treatment: the glaucoma initial treatment study randomised clinical trial

British Journal of Ophthalmology, 2019
Background/AimsTo determine if selective laser trabeculoplasty (SLT) is superior to topical medication as a first-line treatment for glaucoma on quality of life (QoL) and clinical outcomes.MethodsIn this international, longitudinal, multisite randomised controlled trial, treatment naïve mild-to-moderate primary open angle or exfoliation glaucoma ...
Ghee Soon Ang   +19 more
openaire   +3 more sources

Topical herbal application as an adjuvant treatment for chronic kidney disease – a systematic review of randomized controlled clinical trials

Journal of Advanced Nursing, 2012
zhang h., ho y.f., che c.‐t., lin z.‐x., leung c. & chan l.s. (2012) Topical herbal application as an adjuvant treatment for chronic kidney disease – a systematic review of randomized controlled clinical trials. Journal of Advanced Nursing68(6), 1679–1691.AbstractAim.  To report a systematic review to evaluate whether topical herbal medicine delays
Hongwei, Zhang   +5 more
openaire   +2 more sources

Topical ketorolac as an adjunctive treatment with intravitreal bevacizumab in the management of diabetic macular edema: A double-masked placebo-controlled randomized clinical trial

Graefe's Archive for Clinical and Experimental Ophthalmology, 2021
To evaluate the additional effect of ketorolac eye drops on therapeutic effects of intravitreal Bevacizumab in patients with diabetic macular edema (DME) METHODS: In a randomized clinical trial, 50 patients with center involved DME (macular thickness ≥ 300 microns accompanied by decreased VA (24 
Homayoun Nikkhah   +6 more
openaire   +2 more sources

A pilot clinical trial testing topical resiquimod and a xenopeptide as immune adjuvants for a melanoma vaccine targeting MART-1

Melanoma Research, 2019
A vaccine that could expand melanoma-specific T cells might reduce the risk of recurrence of resected melanoma and could provide an alternative or adjunct to standard immunotherapy options. We tested the safety and immunogenicity of a vaccine coupling a melanoma-associated peptide with a xenogenic peptide (to promote epitope spreading) and/or ...
Matthew S, Block   +5 more
openaire   +2 more sources

Efficacy and Safety of Topical Pidobenzone 4% as Adjuvant Treatment for Solar Lentigines: Result of a Randomized, Controlled, Clinical Trial

Dermatology, 2016
<b><i>Background/Objective:</i></b> This study aims at the evaluation of the efficacy and safety of a combination therapy based on pidobenzone 4% and fractional CO<sub>2</sub> laser or cryotherapy in the treatment of solar lentigines and the prevention of eventual posttreatment hyperchromia. <b><i>Methods:
Anna, Campanati   +9 more
openaire   +2 more sources

The first clinical trial of topical application of procyanidin B‐2 to investigate its potential as a hair growing agent

Phytotherapy Research, 2001
AbstractProcyanidin B‐2 is a compound we have identified in apple which acts as a growth‐promoting factor on murine hair epithelial cells. This report describes our investigation of the hair‐growing effects of 1% procyanidin B‐2 tonic after sequential use for 4 months.
T, Takahashi   +4 more
openaire   +2 more sources

Effectiveness of topical haemocoagulase as a haemostatic agent in children undergoing extraction of primary teeth: a split-mouth, randomised, double-blind, clinical trial

European Archives of Paediatric Dentistry, 2019
To assess the effectiveness of topically-administered haemocoagulase (batroxobin) (HC) following dental extractions in children.Split-mouth design, where either HC (test) or Normal Saline (control) (NS) was administered to children (5-9 years) requiring bilateral extractions of primary molars.
D. F. Swamy   +2 more
openaire   +2 more sources

Tetracaine hydrochloride 0.5% versus lidocaine 2% jelly as a topical anesthetic agent in cataract surgery

Journal of Cataract and Refractive Surgery, 2007
To assess the anesthetic efficacy of tetracaine hydrochloride 0.5% (TetraVisc) versus lidocaine 2% jelly in routine cataract extraction.Private surgicenter, Warwick, Rhode Island, USA.A prospective randomized double-blind clinical trial comprised 100 patients having routine cataract extraction by clear corneal phacoemulsification.
Howard, Amiel, Paul S, Koch
openaire   +2 more sources

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