Results 81 to 90 of about 18,378,232 (237)

Surgical Considerations in Portal Hypertension. [PDF]

This review provides an in-depth exploration of portal hypertension (PH) and its implications in various surgical procedures. The prevalence of clinically significant PH is 50% to 60% in compensated cirrhosis and 100% in decompensated cirrhosis.
Berzigotti, Annalisa, Ma, Ann Thu, Sapisochin, Gonzalo, Li, Zhihao, Choi, Woo Jin, Gaviria, Felipe, Magyar, Christian Tibor Josef   +6 more
core   +1 more source

Engineered molecular diagnostic strategies for hepatocellular carcinoma: Integrating flexible photonic barcodes, liquid biopsies, and AI‐enhanced sensing platforms

FlexMat, EarlyView.
Abstract Early diagnosis of hepatocellular carcinoma (HCC) remains challenging because conventional serum biomarkers, especially alpha‐fetoprotein (AFP), show limited sensitivity for early‐stage disease. Recent progress in engineered molecular diagnostics provides new opportunities to improve HCC detection through integrated material, molecular, and ...
Jingzhi Xue, Wanqi Yang, Xiaoyu Liu, Xuehui Chu, Wei Li, Jinglin Wang   +5 more
wiley   +1 more source

Recent Advances in the Pathogenesis and Clinical Evaluation of Portal Hypertension in Chronic Liver Disease

Gut and Liver
In chronic liver disease, hepatic stellate cell activation and degeneration of liver sinusoidal endothelial cells lead to structural changes, which are secondary to fibrosis and the presence of regenerative nodules in the sinusoids, and to functional ...
Kohei Kotani, Norifumi Kawada
doaj   +1 more source

Digital Healthy Aging in China: Current Landscape and the Way Forward

Health Care Science, EarlyView.
This review illustrates China's journey toward digital healthy aging, navigating the challenges of population aging through national strategies and innovative digital technologies to enable integrated, personalized care for older adults. ABSTRACT China is experiencing rapid population aging, which poses increasing challenges for healthcare and social ...
Yingpeng Qiu, Han Yao, Ping Ren, Xueqing Tian, Xuefei Gu   +4 more
wiley   +1 more source

The portal hypertension syndrome: etiology, classification, relevance, and animal models. [PDF]

, 2017
BACKGROUND Portal hypertension is a key complication of portal hypertension, which is responsible for the development of varices, ascites, bleeding, and hepatic encephalopathy, which, in turn, cause a high mortality and requirement for liver ...
Iwakiri, Yasuko, Jaime Bosch, Bosch, Jaime, Yasuko Iwakiri   +3 more
core   +1 more source

Decompensation in Direct-Acting Antiviral Cured Hepatitis C Virus Compensated Patients With Clinically Significant Portal Hypertension: Too Rare to Warrant Universal Β-Blocker Therapy

, 2021
Nonselective β-blockers improve decompensation-free survival in viremic hepatitis C virus compensated cirrhotic patients with clinically significant portal hypertension, but their protective role after sustained virological response by direct-acting ...
Farina E., Degasperi E., Soffredini R., Primignani M., Borghi M., Lampertico P., D'Ambrosio R., Tosetti G., La Mura V.   +8 more
core   +1 more source

Model for End‐Stage Liver Disease/Pediatric End‐Stage Liver Disease exception policy and outcomes in pediatric patients with hepatopulmonary syndrome requiring liver transplantation

Liver Transplantation, EarlyView., 2022
Abstract Hepatopulmonary syndrome (HPS) is associated with increased waitlist mortality in liver transplantation (LT) candidates. Children with HPS are granted Model for End‐Stage Liver Disease (MELD)/Pediatric End‐Stage Liver Disease (PELD) exception points for waitlist prioritization in the United States based on criterion developed for adults.
Muhammad H. Raza, Yong Kwon, Pierre Kobierski, Asish C. Misra, Angelina Lim, Cameron Goldbeck, Kambiz Etesami, Rohit Kohli, Juliet Emamaullee   +8 more
wiley   +1 more source

Blood-based Vienna 3P/5P risk models accurately predict first hepatic decompensation in compensated advanced chronic liver disease

JHEP Reports
Background & Aims: Invasive measurement of hepatic venous pressure gradient (HVPG) is the gold standard for diagnosing clinically significant portal hypertension (CSPH, i.e. HVPG ≥10 mmHg), which indicates an increased risk of decompensation.
Georg Kramer, Benedikt Simbrunner, Mathias Jachs, Lorenz Balcar, Benedikt Silvester Hofer, Nina Dominik, Lukas Hartl, Michael Schwarz, Georg Semmler, Christian Sebesta, Paul Thöne, Sophia Geisselbrecht, Benjamin Maasoumy, Eduardo Alvarez, Martin Sebastian McCoy, Oleksandr Petrenko, Jiří Reiniš, Philipp Schwabl, Albert F. Stättermayer, Michael Trauner, Mattias Mandorfer, Thomas Reiberger   +21 more
doaj   +1 more source

Clinically significant change in stroke volume in pulmonary hypertension

, 2011
Background: Stroke volume is probably the best hemodynamic parameter because it reflects therapeutic changes and contains prognostic information in pulmonary hypertension (PH). Stroke volume directly reflects right ventricular function in response to its
Mauritz, G.J., J. Tim Marcus, Gert-Jan Mauritz, Anco Boonstra, Wouter Jacobs, Marques, K.M.J., Jean G.F. Bronzwaer, Marcus, J.T., Marielle C. van de Veerdonk, van de Veerdonk, M.C., Jacobs, W., van Wolferen, S.A., Bronzwaer, J.G.F., Postmus, P.E., Martijn W. Heymans, Noordegraaf, A.V., Serge A. van Wolferen, Heijmans, M.W., Westerhof, N., Nico Westerhof, Boonstra, A., Koen M.J. Marques, Pieter E. Postmus, Anton Vonk Noordegraaf   +23 more
core   +1 more source

Evaluation of liver stiffness measurement–based scores in liver transplantation recipients

Liver Transplantation, EarlyView., 2022
Abstract Combining bioclinical parameters with liver stiffness measurement (LSM) has improved the diagnostic performance of vibration‐controlled transient elastography (VCTE) for detection of advanced fibrosis in patients with chronic liver disease. However, this approach has not yet been tested in liver transplantation (LT) recipients.
Tamoore Arshad, Chandra S. Bhati, Anh T. Bui, Michael Tseng, Dylan Vainer, Austin Miller, Marie‐Claire Evans, Taseen Syed, Vaishali Patel, Michael O. Idowu, Mark Muthiah, Mohammad Shadab Siddiqui   +11 more
wiley   +1 more source