Results 121 to 130 of about 88,264 (269)

Ibrutinib versus allogeneic haematopoietic stem cell transplant in relapsed/refractory del(17p) chronic lymphocytic leukaemia/small lymphocytic lymphoma

open access: yesBritish Journal of Haematology, EarlyView.
After adjusting for confounders, the ibrutinib cohort had significantly better overall survival (adjusted hazard ratio, 0.39; 95% confidence interval, 0.23–0.68; p = 0.0008) than the allogeneic haematopoietic stem cell transplantation (alloHSCT) cohort.
Farrukh T. Awan   +8 more
wiley   +1 more source

sj-xls-1-cll-10.1177_09636897241231892 – Supplemental material for The Progress and Prospects of Immune Cell Therapy for the Treatment of Cancer

open access: yes
Supplemental material, sj-xls-1-cll-10.1177_09636897241231892 for The Progress and Prospects of Immune Cell Therapy for the Treatment of Cancer by Jia Han, Bowen Zhang, Senyu Zheng, Yuan Jiang, Xiaopeng Zhang and Kaiyun Mao in Cell ...
Jia Han (451925)   +5 more
core   +1 more source

Dynamic risk stratification using early CAR‐T expansion in R/R LBCL treated with axicabtagene ciloleucel

open access: yesBritish Journal of Haematology, EarlyView.
Higher chimeric antigen receptor‐T expansion at day 7 is associated with improved progression‐free survival but also increased toxicity in axi‐cel treated patients with R/R large B‐cell lymphoma, independent of other baseline patient and disease characteristics.
Brydon Panozzo   +17 more
wiley   +1 more source

Lenalidomide maintenance after initial immunochemotherapy in chronic lymphocytic leukaemia—Final analysis of the international phase III CLL6 RESIDUUM study of the ALLG and FILO groups

open access: yesBritish Journal of Haematology, EarlyView.
Summary Most patients treated for chronic lymphocytic leukaemia (CLL) fail to achieve measurable residual disease (MRD) negativity. The role of maintenance with the immunomodulatory drug lenalidomide in these patients is unclear. A randomised multicentre phase III trial (ACTRN12610000060044) was conducted in Australia and France to assess the effect of
Thérèse Aurran‐Schleinitz   +45 more
wiley   +1 more source

Chronic Lymphocytic Leukemia with Dermatomyositis: A Therapeutic Challenge

open access: yesTurkish Journal of Hematology, 2020
Sudhir Kumar   +3 more
doaj   +1 more source

On the asymmetry, complexity and predicted data patterns of nontraditional item response theory models

open access: yesBritish Journal of Mathematical and Statistical Psychology, EarlyView.
Abstract Traditional item response theory (IRT) models involve symmetric response probability functions, but a developing area of research has focused on asymmetric alternatives. To date, these studies have focused primarily on introducing new asymmetric models, detailing their mathematical formulations, explaining how to interpret their item ...
Hyejin Shim, Wes Bonifay
wiley   +1 more source

The role of the adenosinergic pathway in resistance to hypomethylating agents in patients with high‐risk myelodysplastic syndromes

open access: yes
British Journal of Haematology, EarlyView.
George Vrachiolias   +15 more
wiley   +1 more source

Thermodynamic characterisation of covalent ligand binding

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Differential scanning fluorimetry (DSF) is a common and straightforward method to evaluate the thermal stability of proteins and has been heavily used for ligand binding characterisation as well as for screening. One class of compounds that is less typically evaluated by DSF are covalent binders.
Rebecca Hertzman   +4 more
wiley   +1 more source

Folate receptors detection based on the immobilization of folic acid onto Ti−W oxides thin film

open access: yesBiosensors and Bioelectronics: X
The overexpression of folate receptors on cell surfaces is associated with abnormalities linked to epithelial cancers. This study reports on a capacitive biosensor that employs folic acid as a recognition molecule for the biosensing of folate receptors ...
Linda Bertel   +3 more
doaj   +1 more source

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