Results 161 to 170 of about 252,165 (283)

Supplementary Table 1 from Mechanisms of Action of a Dual Cdc7/Cdk9 Kinase Inhibitor against Quiescent and Proliferating CLL Cells

open access: gold, 2023
Alessandro Natoni   +7 more
openalex   +1 more source

Impact of Adolescent and Young Adult Cancer Expertise in Oncologists on AYA Outcomes in Hodgkin Lymphoma: A Population‐Based Study in Ontario, Canada

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Purpose To determine whether adolescent and young adults (AYA) with Hodgkin lymphoma (HL) who are treated by oncologists with “AYA expertise” improve outcomes. Methods All AYA aged 15–21 years diagnosed with HL in Ontario, Canada between 1992 and 2012 were identified, and clinical data abstracted as part of the IMPACT cohort.
Eden C. Andrew   +5 more
wiley   +1 more source

Preclinical development of ARD103, a CLL-1 CAR-T produced by a 3-day DashCAR technology, for acute myeloid leukemia.

open access: gold, 2023
Chien‐Tsun Kuan   +4 more
openalex   +1 more source

Ibrutinib sensitizes CLL cells to venetoclax by interrupting TLR9-induced CD40 upregulation and protein translation [PDF]

open access: hybrid, 2023
Karoline Kielbassa   +10 more
openalex   +1 more source

Function of B-Cell CLL/Lymphoma 11B in Glial Progenitor Proliferation and Oligodendrocyte Maturation

open access: gold, 2018
Chih-Yen Wang   +5 more
openalex   +1 more source

Minimal residual disease in solid tumors: Clinical applications and future directions

open access: yesCancer, Volume 132, Issue 3, 1 February 2026.
Abstract Minimal residual disease (MRD) refers to the presence of residual cancer cells or tumor‐derived fragments that persist after treatment and remain undetectable by conventional imaging or protein‐based assays. Circulating tumor DNA (ctDNA) has emerged as a dynamic biomarker for MRD detection.
Theresa Abdo   +8 more
wiley   +1 more source

An unusual presentation of Chronic Lymphocytic Leukaemia as delirium

open access: yesArchives of Mental Health, 2017
Delirium is a state of impairment in the level of consciousness, cognition, psychomotor activity, sleep-wake cycle and emotions. It is one of the most common neuropsychiatric complication in terminally ill cancer patients. People with Chronic Lymphocytic
N Manamohan   +3 more
doaj  

WRAP53 is Downregulated in Acute Myeloid Leukemia Patients and Positively Correlates With HTERT Expression

open access: yesCancer Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Acute myeloid leukemia (AML) is a prevalent hematologic malignancy in adults, marked by clonal disorders in hematopoietic cells, rapid progression, and genetic heterogeneity. The WRAP53 gene, which is associated with genomic stability due to its involvement in activities, such as DNA repair, TP53 regulation, and association with ...
Renan Brito Gadelha   +14 more
wiley   +1 more source

Overcoming challenges in CAR‐T therapy for malignancies: Mechanisms and strategies

open access: yesClinical and Translational Discovery, Volume 6, Issue 1, February 2026.
Chimeric antigen receptor T (CAR‐T) cell therapy faces three major challenges: tumour‐intrinsic resistance mechanisms, limitations in CAR‐T cell efficacy and immunosuppressive tumour microenvironment (TME) effects. Emerging strategies address these hurdles through precision targeting enhancement, optimised CAR‐T cell persistence/functionality and TME ...
Yushan Huang   +7 more
wiley   +1 more source

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