Results 151 to 160 of about 242,018 (254)

Chronic lymphocytic leukemia with IGH::BCL3‐translocation is characterized by a homogeneous and distinct genetic and epigenetic landscape

open access: yesHemaSphere, Volume 10, Issue 5, May 2026.
Abstract Approximately 1% of chronic lymphocytic leukemia (CLL) cases harbor a translocation juxtaposing the immunoglobulin heavy chain (IGH) and B‐cell lymphoma 3 (BCL3) loci. Aiming at comprehensive molecular characterization of IGH::BCL3‐positive B‐cell neoplasms, we here investigated samples from 84 patients using fluorescence in situ hybridization
Cosima Drewes   +24 more
wiley   +1 more source

Outcomes of patients with CLL and borderline IGHV mutational status: a systematic review and meta analysis. [PDF]

open access: yesBiomark Res
Angotzi F   +12 more
europepmc   +1 more source

CRISPR Genome Editing and the Future of Leukaemia Immunotherapy

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Leukaemia presents ongoing therapeutic challenges due to relapse and toxicity associated with standard treatments. By enabling more targeted and safer therapies, CRISPR genome editing is emerging as a powerful tool to address these issues.
Dejin Rai, Umberto Terranova
wiley   +1 more source

Direct‐stick embolization to treat hematochezia secondary to rectally metastatic sacral neuroblastoma

open access: yesJPGN Reports, Volume 7, Issue 2, Page 281-284, May 2026.
Abstract Neuroblastoma is a malignant tumor that is typically treated with a combination of surgery, radiation therapy, chemotherapy, and immunotherapy. However, minimally invasive embolization and chemoembolization present promising new treatment modalities.
Anand Dhatt   +4 more
wiley   +1 more source

Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang   +6 more
wiley   +1 more source

CLL

open access: yesAnnals of Oncology, 2011
openaire   +2 more sources

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