Results 161 to 170 of about 88,264 (269)
Chronic lymphocytic Leukaemia (CLL) is a B-cell malignancy marked by biological heterogeneity, variable progression and survival outcomes. Orphan toll-like receptor CD180 (RP105) complexed with the accessory protein MD-1 and CD150, which belongs to the ...
Emanuela V. Volpi +8 more
core +1 more source
During the 2023–2024 Argentine dengue outbreak, 33 patients with hematological disease showed high complication rates, frequent hospitalization (64%), severe thrombocytopenia (90%), and 6% dengue‐attributable mortality. Transfusion‐associated cases were documented.
Gustavo Adolfo Méndez +16 more
wiley +1 more source
In adults with hematologic malignancies, RSV vaccination was safe and induced antibody and T‐cell responses. However, antibody levels were lower and declined more rapidly than in healthy controls. While early immune responses were evident, reduced magnitude and durability of protection suggest the need for optimized vaccination strategies in this high ...
Alisse Hannaford +32 more
wiley +1 more source
Nucleolin Alterations and ROS Production Associate With Sensitivity of AML Cells to Venetoclax
Venetoclax‐induced Bcl‐2 inhibition corresponds with Mcl‐1 attenuation and decrease of Nucleolin (NCL) level and activity in sensitive cells. Simultaneously, distinct cell subpopulations with opposite mitochondrial (CellROX label, magenta) and cellular (H2DCFDA stain, green) ROS occur, and the H2DCFDA‐positive population shows markers of early ...
Kateřina Wolfová +2 more
wiley +1 more source
Circulating Extracellular Vesicle Biomarkers in Chronic Lymphocytic Leukemia: A Preliminary Study on Their Diagnostic, Prognostic, and Predictive Relevance. [PDF]
Laurenzana I +9 more
europepmc +1 more source
Aim Meropenem is a second‐line antimicrobial agent in the treatment of febrile neutropenia in onco‐haematological patients. A population pharmacokinetic/pharmacodynamic (PK/PD) analysis for assessing the relationship between meropenem exposure and C‐reactive protein (C‐RP) over time was conducted.
Chun Liu +7 more
wiley +1 more source
Early-onset CLL is characterized by enhanced microenvironment-driven metabolic fitness, increased proliferative bias, and accelerated disease progression. [PDF]
Payque E +15 more
europepmc +1 more source
ABSTRACT The rapid global expansion of photovoltaic (PV) solar facilities, now comprising nearly 80% of the recent and projected growth of renewable electricity, represents one of the most significant land‐use changes of the 21st century. While PV facilities are critical for decarbonising energy systems, their large spatial footprint and infrastructure
Tom Armstrong +4 more
wiley +1 more source
Decoding cancer-associated ribosomal protein mutations: A new frontier in cancer and ribosome biology. [PDF]
Čaušević M, Loewith R, Volarević S.
europepmc +1 more source
Abstract Richter transformation (RT), a highly aggressive lymphoma arising from a preexisting chronic lymphocytic leukemia, represents a major unmet clinical need. Recent data have shown that an antibody–drug conjugate (ADC) targeting the cell‐surface pseudokinase ROR1 is effective in RT patients.
Matilde Micillo +9 more
wiley +1 more source

