Results 181 to 190 of about 252,165 (283)
Body height and the excess cancer risk in men
International Journal of Cancer, Volume 158, Issue 3, Page 597-607, 1 February 2026.What's new?
In cancers that affect both sexes, men usually have a higher risk than women. While this is often attributed to behavioral factors, such as exposure to environmental carcinogens, there may be an intrinsic biological mechanism involved. Tall stature has been associated with increased cancer risk.Cecilia Radkiewicz, Gustaf Edgren, Arvid Sjölander, Emelie Benyi, Mats Lambe, Paul W. Dickman, Lars Sävendahl +6 morewiley +1 more sourceIL21-STAT3 controls the pentose phosphate pathway to support metabolic reprogramming and tumor progression in chronic lymphocytic leukemia. [PDF]
HemasphereDel Prete R, Tusha V, Simon-Molas H, Gazziero VA, Nardi F, Drago R, Bartolini G, Licastro D, Malchiodi M, Mariottini C, Marotta G, Caravagna G, Bruscoli S, Eldering E, Gozzetti A, Bocchia M, Kabanova A. +16 moreeuropepmc +1 more sourceThe proto-oncogene TCL1A deregulates cell cycle and genomic stability in CLL
, 2022 Johanna Stachelscheid, Qu Jiang, Christoph Markus Aszyk, Kathrin Warner, Nadine Bley, Tony Andreas Müller, Olga Vydzhak, Konstantinos Symeonidis, Giuliano Crispatzu, Petra Mayer, Stuart J. Blakemore, Gudrun Goehring, Sebastian Newrzela, Stephanie Hippler, Sandra Robrecht, Karl‐Anton Kreuzer, Christian P. Pallasch, Marcus Krüger, Axel Lechner, Kirsten Fischer, Stephan Stilgenbauer, Dirk Beutner, Michael Hallek, Daniel Auguin, Stefan Hüttelmaier, Johannes Bloehdorn, Elena Vasyutina, Marco Herling +27 moreopenalex +2 more sourcesAntibody‐Targeted Artificial T Cell and Natural Killer Cell Derived Vesicles for Cancer Immunotherapy
Journal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.ABSTRACT T cell and NK92 cell‐derived extracellular vesicles or artificial cell‐derived vesicles (ACDVs) exhibit anti‐cancer effects through inherited cytotoxic proteins like perforin and granzyme or transmembrane receptors like FasL and TRAIL. The anti‐cancer potential of artificial T and NK vesicles has been improved by attaching targeting moieties ...Brijesh Parlekar, David W. Livingstone, Ashley R. Sutherland, Andrés X. Medina, Wendy Bernhard, John DeCoteau, Tays Hernández, Clarence Ronald Geyer +7 morewiley +1 more sourcePS1157 EFFECT OF DOSE MODIFICATIONS ON RESPONSE TO DUVELISIB IN PATIENTS WITH RELAPSED/REFRACTORY CLL/SLL IN THE DUO TRIAL
, 2019 Paolo Ghia, Ian W. Flinn, Nicole Lamanna, Marco Montillo, Árpád Illés, Gabriel Étienne, Julio Delgado, Bryone J. Kuss, Constantine S. Tam, Fritz Offner, F. Bosch, Matthew S. Davids, Ulrich Jäger, Florence Cymbalista, David T. Weaver, Stephanie Lustgarten, Hagop Youssoufian, S. Stilgenbauer +17 moreopenalex +1 more sourceSupplementary Figures S1-S10 from TLR Signaling Is Activated in Lymph Node–Resident CLL Cells and Is Only Partially Inhibited by Ibrutinib
, 2023 Eman L. Dadashian, Erin M. McAuley, Delong Liu, Arthur L. Shaffer, Ryan M. Young, Jessica R. Iyer, Michael J. Kruhlak, Louis M. Staudt, Adrian Wiestner, Sarah E. M. Herman +9 moreopenalex +2 more sourcesOveractivation of Cdc42 GTPase Impairs the Cytotoxic Function of NK Cells From Old Individuals Towards Senescent Fibroblasts
Aging Cell, Volume 25, Issue 2, February 2026.Unrestrained Cdc42 activity causes failure of cytotoxic function of old NK cells. This is associated with disruption of microtubular network and impaired mitochondrial ATP resulting in reduced conjugation and impaired degranulation of lytic vesicles.Albert Kallon Koroma, Karmveer Singh, Yongfang Wang, Linda Krug, Philipp Haas, Meinhard Wlaschek, Vadim Sakk, Tanja Schuster, Daniel Fürst, Hubert Schrezenmeier, Rashmi Priyadharshini Dheenadayalan, Stephan Stilgenbauer, Lutz Walter, Hartmut Geiger, Karin Scharffetter‐Kochanek, Pallab Maity +15 morewiley +1 more source