Results 221 to 230 of about 34,539 (304)

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Electro‐Stimulated Graphene‐Polymer Nanocomposites Enable Wearable Patches With Feedback‐Controlled Drug Release

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Stimuli‐responsive nanomaterials capable of spatiotemporal control over drug release are of nanocomposite patch (“e‐Medi‐Patch”) engineered from biodegradable polycaprolactone (PCL), graphene nanoplatelets, and a redox‐active therapeutic, niclosamide. The hierarchical composite integrates π‐π interactions between aromatic drug molecules
Santosh K. Misra, Ketan Dighe, Pranay Saha, Teresa Aditya, Muhammad S. Khan, Maha Alafeef, Parikshit Moitra, Dipanjan Pan   +7 more
wiley   +1 more source

Methaneseleninic acid, a circadian-modulating agent, reactivates latent HIV-1 infection without cellular activation or proliferation. [PDF]

J Virol
Stern J, Shepherd RA, Kim Y, Tumpach C, Amos KE, Williams OHL, Varshney S, King HAD, Rhodes A, Lewin SR, Roche M.   +10 more
europepmc   +1 more source

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

Advanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter, Abigail R. Fabiano, Ehsan Aalaei, Jason Deng, Dakota E. Rostant, Michael R. King   +5 more
wiley   +1 more source

Dual roles of circadian clock proteins in development and adult homeostasis. [PDF]

NPJ Biol Timing Sleep
Choi M, Liang S, Alvarez-Dominguez JR.
europepmc   +1 more source

Thermal Processing Creates Water‐Stable PEDOT:PSS Films for Bioelectronics

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
Instead of using chemical cross–linkers, it is shown that PEDOT:PSS thin films for bioelectronics become water‐stable after a simple heat treatment. The heat treatment is compatible with a range of rigid and elastomeric substrates and films are stable in vivo for >20 days.
Siddharth Doshi, Margaux O. A. Forner, Pingyu Wang, Salim El Hadwe, Amy T. Jin, Gerwin Dijk, Kenneth Brinson, Juhwan Lim, Antonio Dominguez‐Alfaro, Carina Yi Jing Lim, Alberto Salleo, Damiano G. Barone, Guosong Hong, Mark L. Brongersma, Nicholas A. Melosh, George G. Malliaras, Scott T. Keene   +16 more
wiley   +1 more source

A Codesign Framework for the Development of Next Generation Wearable Computing Systems. [PDF]

Sensors (Basel)
Porreca F, Frustaci F, Gravina R.
europepmc   +1 more source

Two Material Properties from One Wavelength‐Orthogonal Photoresin Enabled by a Monochromatic Laser Integrated Stereolithographic Apparatus (Mono LISA)

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
A single object with dual properties – degradable and non‐degradable – is fabricated in a single print simply by switching the printing colors. The advanced multi‐material printing is enabled by the combination of a fully wavelength‐orthogonal photoresin and a monochromatic tunable laser printer, paving the way for precise multi‐material ...
Xingyu Wu, Katharina Ehrmann, Ching Thye Gan, Benjamin Leuschel, Fred Pashley‐Johnson, Christopher Barner‐Kowollik   +5 more
wiley   +1 more source

Reducing Avalanche Build-Up Time by Integrating a Single-Photon Avalanche Diode with a BiCMOS Gating Circuit. [PDF]

Sensors (Basel)
Goll B, Saadi Nejad M, Schneider-Hornstein K, Zimmermann H.   +3 more
europepmc   +1 more source