Results 91 to 100 of about 159,356 (284)

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Clock Genes, Metabolism, and Cardiovascular Risk [PDF]

open access: yesHeart Failure Clinics, 2017
The molecular clockwork drives rhythmic oscillations of signaling pathways managing intermediate metabolism; the circadian timing system synchronizes behavioral cycles and anabolic/catabolic processes with environmental cues, mainly represented by light/darkness alternation.
Tarquini R., Mazzoccoli G.
openaire   +3 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Watching the hands of the Arabidopsis biological clock [PDF]

open access: yes, 2001
Oligonucleotide and cDNA microarrays have been used to analyse the mRNA levels of 8,000 genes in Arabidopsis thaliana throughout the day/night cycle. Genes involved in signal transduction and in various metabolic pathways were found to be coordinately ...
Davis, Seth J.   +1 more
core   +3 more sources

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Effects of desflurane on central and peripheral clock genes in mice

open access: yesDi-san junyi daxue xuebao, 2019
Objective To investigate the effect and mechanism of the anesthetic drug, desflurane, on central and peripheral clock genes in mice. Methods C57BL/6J mice were anesthetized with different concentrations (3%, 4%, 6%, 7%, 9%) of desflurane, and then the ...
TIAN Hongni   +4 more
doaj   +1 more source

Understanding the role of chromatin remodeling in the regulation of circadian transcription in Drosophila. [PDF]

open access: yes, 2015
Circadian clocks enable organisms to anticipate daily changes in the environment and coordinate temporal rhythms in physiology and behavior with the 24-h day-night cycle. The robust cycling of circadian gene expression is critical for proper timekeeping,
Chiu, Joanna C   +2 more
core   +1 more source

Clock genes, hair growth and aging

open access: yesAging, 2010
Hair follicles undergo continuous cycles of growth, involution and rest. This process, referred to as the hair growth cycle, has a periodicity of weeks to months. At the same time, skin and hair follicles harbor a functional circadian clock that regulates gene expression with a periodicity of approximately twenty four hours.
Geyfman, Mikhail, Andersen, Bogi
openaire   +4 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Phylogenetic footprint of the plant clock system in angiosperms: evolutionary processes of Pseudo-Response Regulators

open access: yesBMC Evolutionary Biology, 2010
Background Plant circadian clocks regulate many photoperiodic and diurnal responses that are conserved among plant species. The plant circadian clock system has been uncovered in the model plant, Arabidopsis thaliana, using genetics and systems biology ...
Saito Shigeru   +3 more
doaj   +1 more source

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