Results 91 to 100 of about 157,763 (284)
Hydra vulgaris exhibits day-night variation in behavior and gene expression levels
Zoological Letters, 2019 Background Day–night behavioral variation is observed in most organisms, and is generally controlled by circadian clocks and/or synchronization to environmental cues.
Hiroyuki J. Kanaya +2 more
doaj +1 more source
BMC Pediatrics, 2023 Background In many organisms, including humans, the timing of cellular processes is regulated by the circadian clock. At the molecular level the core-clock consists of transcriptional-translational-feedback loops including several genes such as BMAL1 ...
Marius Ludwig +4 more
doaj +1 more source
So many genes, so little time: A practical approach to divergence-time estimation in the genomic era [PDF]
, 2018 Phylogenomic datasets have been successfully used to address questions involving evolutionary relationships, patterns of genome structure, signatures of selection, and gene and genome duplications.
Brown, J.W., Smith, S.A., Walker, J.F.
core +1 more source
Clock Genes, Metabolism, and Cardiovascular Risk [PDF]
Heart Failure Clinics, 2017 The molecular clockwork drives rhythmic oscillations of signaling pathways managing intermediate metabolism; the circadian timing system synchronizes behavioral cycles and anabolic/catabolic processes with environmental cues, mainly represented by light/darkness alternation.
Tarquini R., Mazzoccoli G.
openaire +3 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Effects of desflurane on central and peripheral clock genes in mice
Di-san junyi daxue xuebao, 2019 Objective To investigate the effect and mechanism of the anesthetic drug, desflurane, on central and peripheral clock genes in mice. Methods C57BL/6J mice were anesthetized with different concentrations (3%, 4%, 6%, 7%, 9%) of desflurane, and then the ...
TIAN Hongni +4 more
doaj +1 more source
Opportunities for detection and use of QTL influencing seasonal reproduction in sheep: a review [PDF]
, 2004 Genetic improvement in traits associated with seasonal breeding in sheep is challenging because these traits have low heritabilities, are generally not expressed until late in life, are commonly recorded only in females, and are expressed only in some ...
David R Notter, Noelle E Cockett
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Clock genes, hair growth and aging
Aging, 2010 Hair follicles undergo continuous cycles of growth, involution and rest. This process, referred to as the hair growth cycle, has a periodicity of weeks to months. At the same time, skin and hair follicles harbor a functional circadian clock that regulates gene expression with a periodicity of approximately twenty four hours.
Geyfman, Mikhail, Andersen, Bogi
openaire +4 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source