Results 251 to 260 of about 159,356 (284)

Antidepressant mechanism of traditional Chinese medicine: Involving regulation of circadian clock genes. [PDF]

Medicine (Baltimore)
Lv S, Huang Y, Ma Y, Teng J.
europepmc   +1 more source

A New Frontier in Cystic Fibrosis Pathophysiology: How and When Clock Genes Can Affect the Inflammatory/Immune Response in a Genetic Disease Model. [PDF]

Curr Issues Mol Biol
Carbone A, Vitullo P, Di Gioia S, Castellani S, Conese M.   +4 more
europepmc   +1 more source

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Regulation of clock genes

Cellular and Molecular Life Sciences (CMLS), 1999
A recent explosion in the identification of new clock components in cyanobacteria, fungi, insects, mammals as well as potential candidates in plants has uncovered common themes among the structure, function and regulation of these components. Positive and negative interactions that are organized in negative feedback loops have been found crucial for ...
Y, Liu, C, Heintzen, J, Loros, J C, Dunlap   +3 more
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Molecular Clock and Gene Function

Journal of Molecular Evolution, 2003
Molecular phylogenies based on the molecular clock require the comparison of orthologous genes. Orthologous and paralogous genes usually have very different evolutionary fates. In general, orthologs keep the same functions in species, whereas, particularly over a long time span, paralogs diverge functionally and may become pseudogenes or get lost.
Saccone, C., Caggese, C., Lanave, C., Oliva, M., D'ERCHIA, ANNA MARIA, PESOLE, Graziano   +5 more
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Clock genes, ADHD and aggression

Neuroscience & Biobehavioral Reviews, 2018
Attention deficit/hyperactivity disorder (ADHD) is frequently associated with comorbid aggression and sleep disturbances. The sleep/wake cycle is under the control of the circadian system which is moderated by clock genes. Clock genes can regulate the transcription of monoamine oxidase A, which is involved in the degradation of monoamines. Disturbances
Mogavero, Floriana, Jager, Amanda, Glennon, Jeffrey C.   +2 more
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Clock Genes and Clock-Controlled Genes in the Regulation of Metabolic Rhythms

Chronobiology International, 2012
Daily rotation of the Earth on its axis and yearly revolution around the Sun impose to living organisms adaptation to nyctohemeral and seasonal periodicity. Terrestrial life forms have developed endogenous molecular circadian clocks to synchronize their behavioral, biological, and metabolic rhythms to environmental cues, with the aim to perform at ...
Gianluigi, Mazzoccoli, Valerio, Pazienza, Manlio, Vinciguerra   +2 more
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Circadian expression of clock genes and clock-controlled genes in the rat retina

Biochemical and Biophysical Research Communications, 2005
The circadian expression patterns of genes encoding for proteins that make up the core of the circadian clock were measured in rat retina using real-time quantitative PCR (qPCR). Transcript levels of several genes previously used for normalization of qPCR assays were determined and the effect of ischemia-reperfusion on the expression of clock genes was
Kamphuis, Willem, Cailotto, Cathy, Dijk, Frederike, Bergen, Arthur, Buijs, Ruud M.   +4 more
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Circadian clocks: genes, sleep, and cognition

Trends in Cognitive Sciences, 2010
The endogenous circadian clock modulates cognitive performance over the daily 24-h cycle. Environmental disturbance of the clock, such as shift work or jet lag schedules, compromises sleep, alertness and problem solving. What is not generally appreciated, however, is that the circadian clock also modulates cognitive activity independently of time spent
Kyriacou, CP, Hastings, MH
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Clock Genes in Cell Clocks: Roles, Actions, and Mysteries

Journal of Biological Rhythms, 2004
Cellular events must be organized in the time dimension as well as in the space dimension for many proteins to perform their cellular functions effectively. The intracellular molecular oscillating loops that compose the cell’s circadian clock coordinate the timing of the expression of a variety of genes with basic or specific cellular functions.
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