Circadian clock proteins in mood regulation [PDF]
Mood regulation is known to be affected by the change of seasons. Recent research findings have suggested that mood regulation may be influenced by the function of circadian clocks.
Timo ePartonen
doaj +5 more sources
Uncovering the Penile Clock: Expression of Molecular Clock Proteins in Human Penile Cavernous Tissue [PDF]
Purpose: To evaluate the expression of core molecular clock genes/proteins in penile cavernous tissue from healthy male subjects and to determine whether their expression has circadian variation.
Ilter Alkan+5 more
doaj +5 more sources
Abundant clock proteins point to missing molecular regulation in the plant circadian clock [PDF]
Understanding the biochemistry behind whole-organism traits such as flowering time is a longstanding challenge, where mathematical models are critical. Very few models of plant gene circuits use the absolute units required for comparison to biochemical ...
Uriel Urquiza-García+3 more
doaj +3 more sources
Clock Proteins Have the Potential to Improve Term Delivery Date Prediction: A Proof-of-Concept Study [PDF]
Our ability to accurately predict the delivery date of term pregnancies is limited by shortcomings of modern-day clinical tools and due date estimation methods.
Max T. Dufford+11 more
doaj +2 more sources
Melatonin regulates circadian clock proteins expression in allergic airway inflammation [PDF]
Asthma demonstrates a strong circadian rhythm with disrupted molecular clock. Melatonin which can directly regulate circadian rhythm has been reported to alleviate asthma, but whether this effect is related to its regulation on circadian clock has not ...
Si-Nuo Guo+7 more
doaj +2 more sources
Circadian clock proteins in prokaryotes: hidden rhythms? [PDF]
Circadian clock genes are vital features of eukaryotes that have evolved such that organisms can adapt to our planet’s rotation in order to anticipate the coming day or night as well as unfavorable seasons.
Maria eLoza-Correa+5 more
doaj +4 more sources
Clock proteins regulate spatiotemporal organization of clock genes to control circadian rhythms. [PDF]
ABSTRACTCircadian clocks regulate ∼24 hour oscillations in gene expression, behavior, and physiology. While the molecular and neural mechanisms of circadian rhythms are well characterized, how cellular organization of clock components controls circadian clock regulation remains poorly understood. Here, we elucidate how clock proteins regulate circadian
Xiao Y+4 more
europepmc +6 more sources
Clock proteins: Turned over after hours? [PDF]
Light sensitivity and the involvement of unstable proteins are key features of circadian clocks. Both photoreception and ubiquitin conjugation may be associated with nuclear regulators encoded by genes recently identified in Arabidopsis.
Andrew J. Millar
openalex +5 more sources
Expression Patterns of Clock Gene mRNAs and Clock Proteins in Human Psoriatic Skin Samples. [PDF]
Psoriasis is a systemic inflammatory skin disorder that can be associated with sleep disturbance and negatively influence the daily rhythm. The link between the pathomechanism of psoriasis and the circadian rhythm has been suggested by several previous studies. However, there are insufficient data on altered clock mechanisms in psoriasis to prove these
Németh V+4 more
europepmc +4 more sources
Molecular clock in neutral protein evolution. [PDF]
Abstract Background A frequent observation in molecular evolution is that amino-acid substitution rates show an index of dispersion (that is, ratio of variance to mean) substantially larger than one. This observation has been termed the overdispersed molecular clock.
Claus O. Wilke
openalex +8 more sources