Results 11 to 20 of about 127,418 (322)
Circadian clock proteins in prokaryotes: hidden rhythms? [PDF]
Frontiers in Cellular and Infection Microbiology, 2010 Circadian clock genes are vital features of eukaryotes that have evolved such that organisms can adapt to our planet’s rotation in order to anticipate the coming day or night as well as unfavorable seasons.
Maria eLoza-Correa +5 more
doaj +3 more sources
Cold-induced degradation of core clock proteins implements temperature compensation in the Arabidopsis circadian clock. [PDF]
Sci AdvThe period of circadian clocks is maintained at close to 24 hours over a broad range of physiological temperatures due to temperature compensation of period length. Here, we show that the quantitative control of the core clock proteins TIMING OF CAB EXPRESSION 1 [TOC1; also known as PSEUDO-RESPONSE REGULATOR 1 (PRR1)] and PRR5 is crucial ...
Maeda AE +3 more
europepmc +3 more sources
Homeobox-Clock Protein Interaction in Zebrafish [PDF]
Journal of Biological Chemistry, 2005 Lior Appelbaum +3 more
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Investigations of the CLOCK and BMAL1 Proteins Binding to DNA: A Molecular Dynamics Simulation Study. [PDF]
PLoS ONE, 2016 The circadian locomotor output cycles kaput (CLOCK), and brain and muscle ARNT-like 1 (BMAL1) proteins are important transcriptional factors of the endogenous circadian clock.
Tuo Xue +4 more
doaj +1 more source
Journal of Fungi, 2022 FRQ (frequency protein), FRH (FRQ-interacting RNA helicase), and WC1 and WC2 (white collar proteins) are major clock elements that govern the circadian rhythm in Neurosporacrassa. However, deletion of frh is lethal for the viability of N.
Han Peng +3 more
doaj +1 more source
Circadian Clock Proteins and Immunity [PDF]
Immunity, 2014 Immune parameters change with time of day and disruption of circadian rhythms has been linked to inflammatory pathologies. A circadian-clock-controlled immune system might allow an organism to anticipate daily changes in activity and feeding and the associated risk of infection or tissue damage to the host. Responses to bacteria have been shown to vary
Anne M. Curtis +3 more
openaire +4 more sources
Antibodies for assessing circadian clock proteins in the rodent suprachiasmatic nucleus. [PDF]
PLoS ONE, 2012 Research on the mechanisms underlying circadian rhythmicity and the response of brain and body clocks to environmental and physiological challenges requires assessing levels of circadian clock proteins.
Joseph LeSauter +5 more
doaj +1 more source
How is the inner circadian clock controlled by interactive clock proteins? [PDF]
FEBS Letters, 2015 Most internationally travelled researchers will have encountered jetlag. If not, working odd hours makes most of us feel somehow dysfunctional. How can all this be linked to circadian rhythms and circadian clocks? In this review, we define circadian clocks, their composition and underlying molecular mechanisms.
Merbitz-Zahradnik, Torsten, Wolf, Eva
openaire +2 more sources
ASMT Regulates Tumor Metastasis Through the Circadian Clock System in Triple-Negative Breast Cancer
Frontiers in Oncology, 2020 ObjectiveTriple-negative (PR−, ER−, HER-2−) breast cancer (TNBC) is regarded as more aggressive and more likely to recur after medical care. Emerging evidence has demonstrated that the circadian clock system regulates cell-signaling pathways critical to ...
FenFen Xie +21 more
doaj +1 more source
The Clock Proteins, Aging, and Tumorigenesis [PDF]
Cold Spring Harbor Symposia on Quantitative Biology, 2007 Many aspects of mammalian physiology and behavior are driven by an intrinsic timekeeping system that has an important role in synchronizing various biological processes within an organism and coordinating them with the environment. It is believed that deregulation of this coordination may cause the development of various pathologies.
R V, Kondratov, M P, Antoch
openaire +2 more sources