Results 71 to 80 of about 43,948 (302)
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
CLOGGING POTENTIAL OF PERMEABLE CONCRETE [PDF]
, 2017 Permeable concrete is used to reduce local flooding in urban areas. However, it is prone to clogging by particulate matter and requires regular maintenance.
Kia, A, Wong, H, Cheeseman, CR
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Clogging of granular hopper flows [PDF]
, 2015 This work focuses on the clogging of granular materials. Dynamic arrest in granular systems continues to elude a comprehensive description. We consider gravity-driven flow from a hopper as a quintessential example of a system that can spontaneously ...
Thomas, Charles C, Thomas, Charles
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Journal of Fluid Mechanics, 2022 Viscoplastic materials cannot flow if the local stress falls below the yield stress of the material. Such materials tend to ‘clog up’ geometrical features like corners or side branches by forming rigid plugs, because the stress becomes insufficient to yield them. In this volume, Taylor-West and Hogg (J. Fluid Mech., vol.
openaire +3 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Clogging in permeable concrete: a review [PDF]
, 2017 Permeable concrete (or “pervious concrete” in North America) is used to reduce local flooding in urban areas and is an important sustainable urban drainage system.
Alalea Kia +5 more
core +1 more source
The Effect of Emitter Spacing on Physical Clogging of Drip Irrigation Tapes
علوم آب و خاک, 2017 Drip irrigation is one of the new irrigation methods for optimum use of water resources and increase of irrigation efficiency. The emitterschr('39') clogging is the most important problem in these systems.
C. Abdi, P. Fathi
doaj