Results 211 to 220 of about 3,725,865 (331)

Clonal expansion of cytotoxic CD8⁺ T cells in lecanemab-associated ARIA. [PDF]

Nat Commun
Johnson LA, Saito K, Pallerla AV, Funnell JL, Ezzo AR, Song CM, Harrison DA, Norton NJ, Moore LC, Van Eldik LJ, Fardo DW, Cooper GE, Morganti JM.   +12 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Belowground clonal expansion and biomass allocation of Phragmites australis along a sand burial gradient in mobile dunes. [PDF]

BMC Plant Biol
Ba C, Jia R, Liu Z, Qian J, Yang Y, Xin Z, Liu B, Zhou Q, Liu Y, Xue Z.   +9 more
europepmc   +1 more source

Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells

Journal of Clinical Investigation, 2017
Guinevere Q. Lee, Nina Orlova-Fink, K. Einkauf, Fatema Z. Chowdhury, Xiao-Ming Sun, S. Harrington, H. Kuo, S. Hua, Hsiao-Rong Chen, Zheng-Yu Ouyang, K. Reddy, Krista L. Dong, T. Ndung'u, B. Walker, E. Rosenberg, Xu G. Yu, M. Lichterfeld   +16 more
semanticscholar   +1 more source

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops

Advanced Science, EarlyView.
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang, Yupo Wu, Jiachang Hou, Lixia Gao, Longqi Pan, Cuicui Shen, Chuanji Zhao, Feng Gao, Yi Zhang, Li Ren, Xiaoping Fang, Xiaoling Dun, Shengyi Liu, Lijiang Liu   +13 more
wiley   +1 more source

Trisomy 8 clonal expansion during disease progression and azacitidine resistance in VEXAS syndrome: a case report. [PDF]

Front Immunol
Sato K, Zaimoku Y, Kano Y, Kobayashi M, Kazama S, Morikawa T, Kazumoto H, Ishii W, Ueki T, Sumi M, Kobayashi H, Nannya Y, Ogawa S, Ichikawa N.   +13 more
europepmc   +1 more source

Overcoming Artificial Structures in Resolution‐Enhanced Hi‐C Data by Signal Decomposition and Multi‐Scale Attention

Advanced Science, EarlyView.
Deep‐learning‐based signal enhancement is an effective way to recover high‐resolution details from a low‐resolution chromatin contact map. However, due to computational challenges, existing methods commonly divide up the contact map into small patches and create artificial discontinuities at patch boundaries.
Qinyao Li, Kelly Yichen Li, Chiara Nicoletti, Stephen Kwok‐Wing Tsui, Pier Lorenzo Puri, Qin Cao, Kevin Y. Yip   +6 more
wiley   +1 more source

Non-canonical clonal expansion of autoreactive CD8⁺ T cells following influenza infection. [PDF]

Cell Insight
Hou S, Qi H.
europepmc   +1 more source

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

Advanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang, Jiani Deng, Man Yee Cheung, Tingting Fu, Xufeng Qi, Dongqing Cai, Jianmin Sun, Gang Lu, Peng Shi, Wai‐Yee Chan, Xu Li, Hui Zhao   +11 more
wiley   +1 more source

Persistent interferon signaling and clonal expansion mark early events in DNA methylation damage-induced liver cancer. [PDF]

NAR Cancer
Pribyl LJ, Kay JE, Corrigan JJ, Volk LB, Norales M, Owiti NA, Kowal EA, Kohale IN, Nazari IS, Swanson MR, Moise AC, Ma D, Levine SS, Michelsen EM, Croy RG, Ragan T, Torous DK, Avlasevich SL, Dertinger SD, Carrasco SE, Samson LD, Essigmann JM, White FM, Engelward BP.   +23 more
europepmc   +1 more source