Results 291 to 300 of about 2,119,256 (322)

Spontaneous high clonal expansion of Wilms' tumor gene 1-specific cytotoxic T-lymphocytes in patients with Wilms' tumor gene 1-expressing solid tumor. [PDF]

Cancer Immunol Immunother
Morimoto S, Tanaka Y, Nakata J, Fujiki F, Hasegawa K, Nakajima H, Nishida S, Tsuboi A, Hosen N, Kagawa N, Maruno M, Myoui A, Enomoto T, Izumoto S, Sekimoto M, Hashimoto N, Yoshimine T, Kumanogoh A, Oji Y, Oka Y, Sugiyama H.   +20 more
europepmc   +1 more source

TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration

Advanced Science, EarlyView.
Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera, Lena Kühn, Lisa Jungbluth, Verian Bader, Laura J. Krause, David Kartte, Elias Adriaenssens, Sascha Martens, Jörg Tatzelt, Carsten Sachse, Konstanze F. Winklhofer   +10 more
wiley   +1 more source

Single-cell RNA-seq reveals disease-specific CD8+ T cell clonal expansion and a high frequency of transcriptionally distinct double-negative T cells in diabetic NOD mice. [PDF]

PLoS One
Islam MZ, Zimmerman S, Lindahl A, Weidanz J, Ordovas-Montanes J, Kostic A, Luber J, Robben M.   +7 more
europepmc   +1 more source

A retinoid analogue, TTNPB, promotes clonal expansion of human pluripotent stem cells by upregulating CLDN2 and HoxA1. [PDF]

Commun Biol
Nath SC, Babaei-Abraki S, Meng G, Heale KA, Hsu CYM, Rancourt DE.   +5 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Clonal expansion in non-cancer tissues

Nature Reviews Cancer, 2021
Cancer is a clonal disorder derived from a single ancestor cell and its progenies that are positively selected by acquisition of 'driver mutations'. However, the evolution of positively selected clones does not necessarily imply the presence of cancer.
Nobuyuki Kakiuchi, Seishi Ogawa
openaire   +3 more sources

Clonal expansion of innate and adaptive lymphocytes

Nature Reviews Immunology, 2020
One of the hallmarks of the vertebrate adaptive immune system is the prolific expansion of individual cell clones that encounter their cognate antigen. More recently, however, there is growing evidence for the clonal expansion of innate lymphocytes, particularly in the context of pathogen challenge.
Nicholas M. Adams, Simon Grassmann, Joseph C. Sun   +2 more
openaire   +3 more sources

Clonal Expansion

Definitions, 2020
openaire   +2 more sources

Macroscopic somatic clonal expansion in morphologically normal human urothelium

Science, 2020
Genetic profiles of the bladder Depending on the environment of the individual, the human bladder can be exposed to carcinogens as they are flushed through the body. Lawson et al. and Li et al.
Ruoyan Li, Yiqing Du, Zhanghua Chen, Deshu Xu, Tianxin Lin, Shanzhao Jin, Gongwei Wang, Ziyang Liu, Min Lu, Xu Chen, Tao Xu, F. Bai   +11 more
semanticscholar   +1 more source

Modeling Clonal Expansion from M-FISH Experiments

Journal of Computational Biology, 2008
A population genetic model is used to describe dynamical aspects of chromosomal abberations observed in M-FISH experiments. Linear differential equations model the evolution of relative frequencies of mutations. The unknown parameters involved are estimated by maximum likelihood methods.
Thomas, Stolte, Volker, Hösel, Johannes, Müller, Michael, Speicher   +3 more
openaire   +2 more sources