Results 281 to 290 of about 3,725,865 (331)

TNF-α signaling drives myeloid skewing and clonal expansion of stem and progenitor cells in <i>RUNX1</i>-familial platelet disorder. [PDF]

Haematologica
Mohammadhosseini M, Sahasrabudhe A, Ostrowski LH, McClatchy J, Knight R, Schabel K, Kagan R, Bresciani E, Liu P, Agarwal A.   +9 more
europepmc   +1 more source

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

Exponential Clonal Expansion of 5-Fluorocytosine-Resistant Candida tropicalis and New Insights into Underlying Molecular Mechanisms. [PDF]

Emerg Infect Dis
Abou-Chakra N, Astvad KMT, Martinussen J, Munksgaard ASE, Arendrup MC.   +4 more
europepmc   +1 more source

Selective Modulation of OTUB1 Noncanonical Function via a bioPhosTAC Strategy

Advanced Science, EarlyView.
This work positions the versatile performance of the peptide‐based bioPhosTAC platform for dissecting phosphorylation‐dependent biology and expanding the scope of induced‐proximity technologies. We demonstrated that selective manipulation of a tyrosine phosphorylation site is sufficient to propagate coordinated cellular consequences.
Seung Un Seo, Seon Min Woo, Minhyeong Choi, Soeun Rhee, Simmyung Yook, Donghyuk Shin, Kwang‐Su Park, Taeg Kyu Kwon   +7 more
wiley   +1 more source

APackOfTheClones: Visualization of clonal expansion with circle packing

Journal of Open Source Software
openaire   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Age-Dependent Clonal Expansion of Non-Sperm-Forming Spermatogonial Stem Cells in Mouse Testes. [PDF]

Aging Cell
Kawahara T, Suzuki S, Nakagawa T, Kamo Y, Kanouchi M, Fujita M, Hattori M, Suzuki A, Tanemura K, Yoshida S, Hara K.   +10 more
europepmc   +1 more source

Plasmid-driven clonal expansion of multidrug-resistant monophasic <i>Salmonella</i> Typhimurium in a Global Food Trade Hub. [PDF]

Emerg Microbes Infect
Huang D, Wu Z, Jiang Y, Hu L, Cai R, Yang X, Du C, Chen S, Yang P, Guo B, Shi X, Wu S, Li Y, Zhou Z, Hu Q.   +14 more
europepmc   +1 more source

STIM2β is a Ca²⁺ signaling modulator for the regulation of mitotic clonal expansion and PPARG2 transcription in adipogenesis. [PDF]

FEBS J
Jeong SJ, Sim BW, Kim SU, Park CY.
europepmc   +1 more source

Multistage carcinogenesis in occupational cholangiocarcinoma: the impact of clonal expansion and risk estimation. [PDF]

Genes Environ
Watanabe M, Haeno H, Mimaki S, Tsuchihara K.   +3 more
europepmc   +1 more source