Results 61 to 70 of about 18,435 (307)
Advanced Science, EarlyView.BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou +9 more
wiley +1 more source
Forest SystemsAim of study: To assess the effectiveness of the mini-cutting technique in propagating a clone of Eucalyptus camaldulensis Dehnh selected in semiarid conditions, test the impact of the growth regulators Indole-3-Acetic Acid (IAA) and Indole-3-Butyric ...
Francisco Emerson F. de Felice +3 more
doaj +1 more source
Advanced Science, EarlyView.To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo +3 more
wiley +1 more source
The effects of clonal forestry on genetic diversity in wild and domesticated stands of forest trees [PDF]
Scandinavian Journal of Forest Research, 2018 The level of genetic diversity maintained in a population is determined by the combined action of mutation, gene flow, genetic drift and selection.
Pär K. Ingvarsson, Helena Dahlberg
openaire +2 more sources
Advanced Science, EarlyView.ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao +14 more
wiley +1 more source
Angewandte Chemie, EarlyView.The self‐adjuvanting vaccine—comprising a covalent conjugate of antigen and adjuvant—was formulated into cationic lipid nanoparticles smaller than 100 nm to facilitate uptake by immune cells, with supplemental adjuvants incorporated to modulate immune responses.
Keita Ito +9 more
wiley +2 more sources
Farming system characterization for rubber smallholders in West Kalimantan [PDF]
, 2003 Dans l'Est-Kalimantan, l'adoption de nouveau matériel végétal dépend de sa disponibilité et du coût, de l'organisation et la cohésion sociale. les exploitants sont , en général, convaincus par les bonnes performances des nouveaux clones d'hévéa.
Courbet, Philippe +2 more
core
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Advanced Science, EarlyView.Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
Advanced Science, EarlyView.In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia +11 more
wiley +1 more source
Research and development of acacia hybrids for commercial planting in Vietnam
Vietnam Journal of Science, Technology and Engineering, 2017 “Acacia hybrids” refers to the inter-specific hybrids of A. mangium and A. auriculiformis, including natural, artificial and polyploid ones. The superiorities of selected acacia hybrid are fast growth, straight stem form, small branches, high ...
Dinh Kha Le, Huy Thinh Ha
doaj +1 more source