Results 141 to 150 of about 102,010 (264)
STAR ProtocolsSummary: Identification of integration sites of human immunodeficiency virus (HIV) is crucial for developing antiretroviral strategies. Here, we present an in vitro transcription-based version of lentiviral integration site sequencing (LIS-seq), enabling
Kamil Więcek +2 more
doaj +1 more source
Approximate model and clonal selection algorithm based optimization of heating channels for variotherm injection mold [PDF]
International Journal of Advanced Design and Manufacturing Technology, 2013 The integration of an approximate model and a clonal selection algorithm (CSA) is considered to one of the most effective ways to solve complex optimization design problems in engineering.
Xiping Li, Ningning Gong, Tingwei Ji
doaj
Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium. [PDF]
, 2018 Adult diffuse gliomas are a diverse group of brain neoplasms that inflict a high emotional toll on patients and their families. The Cancer Genome Atlas and similar projects have provided a comprehensive understanding of the somatic alterations and ...
GLASS Consortium
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Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Integration of biotechnologies for rubber tree improvement. What about rootstock clones ?
, 2008 Breeding and dissemination of planting material for rubber plantations are closely linked to propagation methods. Since the progress made by shifting from multiplication by seed to propagation by budding, the development of new techniques, such as ...
Carron, Marc-Philippe +6 more
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In vivo manipulation of interleukin-2 expression by a retroviral tetracycline (tet)-regulated system [PDF]
, 2006 We have used the tetracycline (tet)-regulated system as described previously to evaluate the applicability of controlled gene expression in cancer gene therapy. As a model gene, we used the human interleukin-2 (IL-2) gene, which has been placed under the
Pitzer, Claudia +4 more
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FEBS Open Bio, EarlyView.This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
THE RUBBER SHOWCASE IN SUMATRA [PDF]
As with cocoa a combination of available land and centres with fairly dense population is a prerequisite for a boom. But in the case of rubber the boom has been far more progressive than that for cocoa due to 3 main factors.
Eric Penot
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